Cancer type ↕ |
Active ingredient ↕ |
Dosage Form(s) and Strength(s) ↕ |
Brand(s) ↕ |
Clinical indication ↕ |
Subsidy Class ↕ |
MediShield Life Claim Limit per month ↕ |
MediSave Withdrawal Limit per month ↕ |
Category ↕ |
Breast cancer |
Abemaciclib |
Abemaciclib tablet (50 mg, 100 mg, 150 mg) |
- |
Abemaciclib in combination with an aromatase inhibitor as initial endocrine-based therapy for HR positive, HER2 negative, advanced or metastatic breast cancer. Pre/perimenopausal women treated with this combination could also receive a luteinizing hormone-releasing hormone agonist according to local clinical practice. |
MAF |
$ 800 |
$ 600 |
4 |
Breast cancer |
Abemaciclib |
Abemaciclib tablet (50 mg, 100 mg, 150 mg) |
- |
Abemaciclib in combination with fulvestrant for treating HR positive, HER2 negative, advanced or metastatic breast cancer in patients who have received prior endocrine therapy. Pre/perimenopausal women treated with this combination could also receive a luteinizing hormone-releasing hormone agonist according to local clinical practice. |
MAF |
$ 800 |
$ 600 |
4 |
Breast cancer | Abemaciclib | Abemaciclib tablet (50 mg, 100 mg, 150 mg)
| - | Abemaciclib in combination with endocrine therapy for adjuvant treatment of patients with HR positive, HER2 negative, node-positive early breast cancer at high risk of recurrence. Maximum treatment duration: 2 years. | MAF | $ 800 | $ 600 | 4 |
Others |
Abiraterone |
Abiraterone tablet (250 mg) |
- |
For cancer treatment. |
SDL
|
$ 400 |
$ 600 |
2 |
Others | Abiraterone | Abiraterone tablet (500 mg, 1000 mg)
| - | For cancer treatment. | No subsidy | $ 400
| $ 600
| 2 |
Leukaemia |
Acalabrutinib |
Acalabrutinib capsule (100 mg), and tablet (100 mg) |
Calquence |
Monotherapy for chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) in patients who have received at least one prior therapy. |
MAF |
$ 2,000 |
$ 600 |
10 |
Leukaemia |
Acalabrutinib |
Acalabrutinib capsule (100 mg), and tablet (100 mg) |
Calquence |
Monotherapy for previously untreated chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) in patients who are unsuitable for fludarabine-based therapy. |
MAF |
$ 2,000 |
$ 600 |
10 |
Lymphoma |
Acalabrutinib |
Acalabrutinib capsule (100 mg), and tablet (100 mg) |
Calquence |
Treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. |
MAF |
$ 2,000 |
$ 600 |
10 |
Leukaemia |
Acalabrutinib plus obinutuzumab
|
Acalabrutinib capsule (100 mg), and tablet (100 mg)
Obinutuzumab concentrate for solution for infusion (1000 mg/40 mL) |
Calquence
Gazyva |
Acalabrutinib in combination with obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) in patients who are unsuitable for fludarabine-based therapy. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Lung cancer |
Afatinib |
Afatinib tablet (20 mg, 30 mg, 40 mg) |
Giotrif |
Treatment of locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer. |
MAF |
$ 600 |
$ 600 |
3 |
Colorectal cancer |
Aflibercept |
Aflibercept concentrate for solution for infusion (100 mg/4 mL) |
Zaltrap |
Aflibercept in combination with FOLFIRI for treating metastatic colorectal cancer that has progressed on first-line systemic therapy. |
No subsidy |
$ 600 |
$ 600 |
3 |
Lung cancer |
Alectinib |
Alectinib capsule (150 mg) |
Alecensa |
Treatment of locally advanced or metastatic ALK mutation-positive non-small-cell lung cancer. |
MAF |
$ 2,000 |
$ 600 |
10 |
Breast cancer |
Alpelisib |
Alpelisib tablet (150 mg, 200 mg, 200mg + 50 mg pack) |
Piqray |
Alpelisib in combination with fulvestrant for treating HR-positive, HER2-negative, advanced breast cancer in patients with a PIK3CA mutation after disease progression following an endocrine-based regimen. |
No subsidy |
$ 800 |
$ 600 |
4 |
Myeloproliferative neoplasms |
Anagrelide |
Anagrelide capsule (0.5 mg) |
Agrylin |
Reduction of elevated platelet counts in patients with essential thrombocythaemia who are intolerant to their existing therapy or for whom other therapies are not considered appropriate. |
MAF |
$ 200 |
$ 600 |
1 |
Myeloproliferative neoplasms
| Anagrelide | Anagrelide capsule (0.5 mg)
| Agrylin
| Reduction of elevated platelet counts in patients with myeloproliferative neoplasms. | No subsidy | $ 200 | $ 600 | 1 |
Others | Anastrozole |
Anastrozole tablet (1 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Prostate cancer |
Apalutamide |
Apalutamide tablet (60 mg) |
Erleada |
In combination with androgen deprivation therapy (ADT) for treating patients with high-risk non-metastatic castration-resistant prostate cancer (nmCRPC). |
No subsidy |
$ 400 |
$ 600 |
2 |
Prostate cancer |
Apalutamide |
Apalutamide tablet (60 mg) |
Erleada |
In combination with androgen deprivation therapy (ADT) for treating patients with metastatic hormone-sensitive prostate cancer (mHSPC). |
No subsidy |
$ 400 |
$ 600 |
2 |
Others |
Arsenic trioxide |
Arsenic trioxide injection (10 mg) |
- |
For cancer treatment. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Liver cancer |
Atezolizumab plus bevacizumab biosimilar |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL)
Bevacizumab biosimilar concentrate for solution for infusion (100 mg/4 mL, 400 mg/16 mL) |
Tecentriq
Mvasi |
Atezolizumab in combination with bevacizumab biosimilar (subsidised brand) for treating advanced unresectable hepatocellular carcinoma in patients who have not received prior systemic therapy, and who have adequate liver function as assessed by the Child-Pugh scoring system. |
MAF |
$ 3,000 |
$ 600 |
15 |
Lung cancer |
Atezolizumab |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL) |
Tecentriq |
Atezolizumab in combination with a platinum agent and etoposide, for untreated extensive-stage small-cell lung cancer. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Atezolizumab plus bevacizumab biosimilar |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL)
Bevacizumab biosimilar concentrate for solution for infusion (100 mg/4 mL, 400 mg/16 mL) |
Tecentriq
Mvasi |
Atezolizumab in combination with bevacizumab biosimilar (subsidised brand), and platinum-doublet chemotherapy, for the treatment of patients with metastatic non-squamous non-small cell lung cancer (NSCLC) who had not received prior chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for metastatic NSCLC. |
MAF |
$ 3,200 |
$ 600 |
16 |
Lung cancer
| Atezolizumab
| Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL)
| Tecentriq
| Atezolizumab in combination with platinum-doublet chemotherapy, for untreated metastatic non-squamous non-small cell lung cancer (NSCLC), in patients with no EGFR or ALK genomic tumour aberrations.
| MAF | $ 1,800
| $ 600
| 9 |
Lung cancer
| Atezolizumab
| Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL)
| Tecentriq
| Adjuvant treatment following complete resection for patients with Stage II to IIIA non-small cell lung cancer (NSCLC) whose tumours have PD-L1 expression on ≥50% of tumour cells and whose disease has not progressed following platinum-based adjuvant chemotherapy. Maximum duration of treatment: 12 months.
| MAF
| $ 1,800
| $ 600
| 9 |
Lung cancer |
Atezolizumab |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL) |
Tecentriq |
For untreated metastatic non-small cell lung cancer (NSCLC), in patients whose tumours express PD-L1 with a tumour proportion score ≥50%, with no EGFR or ALK genomic tumour aberrations. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Atezolizumab |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL) |
Tecentriq |
Treatment of patients with metastatic non-small cell lung cancer (NSCLC) who have disease progression during or following platinum-containing chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for metastatic NSCLC. |
MAF |
$ 1,800 |
$ 600 |
9 |
Bladder cancer |
Atezolizumab |
Atezolizumab concentrate for solution for infusion (840 mg/14 ml, 1200 mg/20 ml) |
Tecentriq |
Treatment of patients with locally advanced or metastatic urothelial carcinoma (UC) after receiving platinum-containing chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for locally advanced or metastatic UC. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Bladder cancer |
Atezolizumab |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL) |
Tecentriq |
Treatment of patients with locally advanced or metastatic urothelial carcinoma who are not eligible for any platinum-containing chemotherapy regardless of PD-L1 status. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Bladder cancer |
Atezolizumab |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL) |
Tecentriq |
Treatment of patients with locally advanced or metastatic urothelial carcinoma whose tumours express PD-L1 (PD-L1 stained tumour-infiltrating immune cells covering ≥5% of the tumour area), and who are not eligible for cisplatin-containing chemotherapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Breast cancer |
Atezolizumab plus nab-paclitaxel |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL)
Paclitaxel - albumin bound nanoparticles injectable suspension (100 mg) |
Tecentriq
Abraxane |
Atezolizumab in combination with nab-paclitaxel for treating patients with unresectable, locally advanced, or metastatic triple negative breast cancer whose tumours have PD-L1 expression ≥1% and who have not received prior chemotherapy for metastatic disease. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Liver cancer |
Atezolizumab plus bevacizumab |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL)
Bevacizumab concentrate for solution for infusion (100 mg/4 mL, 400 mg/16 mL) |
Tecentriq
Avastin Vegzelma |
Atezolizumab in combination with bevacizumab (non-subsidised brand) for treating advanced unresectable hepatocellular carcinoma in patients who have not received prior systemic therapy, and who have adequate liver function as assessed by the Child-Pugh scoring system. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Lung cancer |
Atezolizumab plus bevacizumab |
Atezolizumab concentrate for solution for infusion (840 mg/14 mL, 1200 mg/20 mL)
Bevacizumab concentrate for solution for infusion (100 mg/4 mL, 400 mg/16 mL) |
Tecentriq
Avastin Vegzelma |
Atezolizumab in combination with bevacizumab (non-subsidised brand), and platinum-doublet chemotherapy, for the treatment of patients with metastatic non-squamous non-small cell lung cancer (NSCLC) who had not received prior chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for metastatic NSCLC. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Bladder cancer |
Avelumab |
Avelumab concentrate for solution for infusion (200 mg/10 mL) |
Bavencio |
Maintenance treatment of locally advanced or metastatic urothelial carcinoma that has not progressed with first-line platinum-based chemotherapy. Avelumab may be given at a dose of 10 mg/kg up to a maximum of 800 mg, every 2 weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Merkel cell cancer |
Avelumab |
Avelumab concentrate for solution for infusion (200 mg/10 mL) |
Bavencio |
Treatment of metastatic merkel cell carcinoma. Avelumab may be given at a dose of 10 mg/kg up to a maximum of 800 mg, every 2 weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Renal cancer |
Avelumab plus axitinib |
Avelumab concentrate for solution for infusion (200 mg/10 mL) Axitinib tablet (1 mg, 5 mg) |
Bavencio Inlyta |
Avelumab in combination with axitinib for untreated advanced renal cell carcinoma. Avelumab may be given at a dose of 10 mg/kg up to a maximum of 800 mg, every 2 weeks. |
MAF |
$ 3,000 |
$ 600 |
15 |
Renal cancer |
Axitinib |
Axitinib tablet (1 mg, 5 mg) |
Inlyta |
For previously treated advanced renal cell carcinoma. |
MAF |
$ 1,000 |
$ 600 |
5 |
Others |
Azacitidine |
Azacitidine injection (100 mg) |
- |
For cancer treatment. |
SDL |
$ 600 |
$ 600 |
3 |
Others |
Bacillus Calmette-Guerin (BCG) |
Bacillus Calmette-Guerin (BCG) solution for intravesical use (12.5 mg, 40 mg, 80 mg) |
- |
For cancer treatment. |
SDL |
$ 600 |
$ 600 |
3 |
Others |
Bendamustine |
Bendamustine concentrate for infusion (25 mg and 100 mg) |
- |
For cancer treatment. |
SDL |
$ 1,000 |
$ 600 |
5 |
Others |
Bevacizumab |
Bevacizumab concentrate for solution for infusion (100 mg/4 mL, 400 mg/16 mL) |
Avastin | For cancer treatment in line with HSA registered indication(s). |
No subsidy |
$ 600 |
$ 600 |
3 |
Others |
Bevacizumab biosimilar |
Bevacizumab biosimilar concentrate for solution for infusion (100 mg/4 mL, 400 mg/16 mL) |
Mvasi |
For cancer treatment. |
SDL (Mvasi) |
$ 600 |
$ 600 |
3 |
Others | Bevacizumab biosimilar | Bevacizumab biosimilar concentrate for solution for infusion (100 mg/4 mL, 400 mg/16 mL)
| Vegzelma | For cancer treatment. | No subsidy | $ 600 | $ 600 | 3 |
Lymphoma |
Bexarotene |
Bexarotene capsule (75 mg) |
- |
Treatment of cutaneous T-cell lymphoma in adults who have received at least one prior systemic therapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Others |
Bicalutamide |
Bicalutamide tablet (50 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Bleomycin |
Bleomycin injection (15 USP unit) |
- |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Leukaemia |
Blinatumomab |
Blinatumomab powder for infusion (35 mcg vial) |
Blincyto |
Treatment of B-precursor acute lymphoblastic leukaemia in first or subsequent complete remission with minimal residual disease (MRD) greater than or equal to 0.1% for: - up to a maximum of one cycle for induction in a lifetime; - and up to three additional cycles for consolidation in a lifetime in patients who are MRD negative. Complete remission is defined as a patient who: a) has 5% or less bone marrow blasts; and b) has no evidence of disease; and c) has a full recovery of peripheral blood counts with platelet count of more than 100,000 per microlitre; and d) absolute neutrophil count of more than 1,000 per microlitre |
MAF |
$ 9,600 |
$ 1,200 |
48 |
Leukaemia |
Blinatumomab |
Blinatumomab powder for infusion (35 mcg vial) |
Blincyto |
Treatment of relapsed or refractory B-precursor acute lymphoblastic leukaemia (r/r B-ALL) for: - up to a maximum of two cycles for induction in a lifetime; and - up to three additional cycles for consolidation in a lifetime in patients who achieve a complete response after induction. Patients with Philadelphia chromosome positive disease must have previously received a tyrosine kinase inhibitor before receiving blinatumomab. Patients must not have received blinatumomab previously for the treatment of minimal residual disease (MRD)-positive B-ALL OR patients must have had a relapse-free period of at least six months following completion of treatment with blinatumomab for MRD. Complete response is defined as a patient who: - has 5% or less bone marrow blasts; and - has no evidence of disease; and - has platelet count of more than 50,000 per microlitre; and - has absolute neutrophil count of more than 500 per microlitre. |
MAF |
$ 9,600 |
$ 1,200 |
48 |
Others |
Bortezomib |
Bortezomib injection (3.5mg) |
- |
For cancer treatment. |
SDL
|
$ 1,400 |
$ 600 |
7 |
Lymphoma |
Brentuximab vedotin |
Brentuximab vedotin powder for concentrate for solution for infusion (50 mg) |
Adcetris |
Brentuximab in combination with cyclophosphamide, doxorubicin and prednisone (CHP), for previously untreated CD30+ peripheral T-cell lymphoma. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Brentuximab vedotin |
Brentuximab vedotin powder for concentrate for solution for infusion (50 mg) |
Adcetris |
Treatment of patients with CD30+ cutaneous T-cell lymphoma who have received at least 1 prior systemic therapy. Treatment should be stopped at 16 cycles, or earlier if disease progresses. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Brentuximab vedotin |
Brentuximab vedotin powder for concentrate for solution for infusion (50 mg) |
Adcetris |
Treatment of patients with relapsed or refractory CD30+ Hodgkin lymphoma (HL): 1. following autologous stem cell transplant (ASCT) or 2. following at least two prior therapies when ASCT or multi-agent chemotherapy is not a treatment option. Treatment should be stopped at 16 cycles, or earlier if disease progresses. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Brentuximab vedotin |
Brentuximab vedotin powder for concentrate for solution for infusion (50 mg) |
Adcetris |
Treatment of relapsed or refractory systemic anaplastic large cell lymphoma. Treatment should be stopped at 16 cycles, or earlier if disease progresses. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Brentuximab vedotin |
Brentuximab vedotin powder for concentrate for solution for infusion (50 mg) |
Adcetris |
Consolidation treatment of patients with CD30+ Hodgkin lymphoma (HL) who are at increased risk of relapse or progression following an autologous stem cell transplant (ASCT). Treatment should be stopped at 16 cycles, or earlier if disease progresses. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Brentuximab vedotin |
Brentuximab vedotin powder for concentrate for solution for infusion (50 mg) |
Adcetris |
Brentuximab vedotin in combination with doxorubicin, vinblastine and dacarbazine (AVD), for treating patients with previously untreated CD30+ advanced classic Hodgkin lymphoma (cHL) who are intolerant or have contraindications to bleomycin. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Brentuximab vedotin |
Brentuximab vedotin powder for concentrate for solution for infusion (50 mg) |
Adcetris |
Brentuximab vedotin in combination with doxorubicin, vinblastine and dacarbazine (AVD), for treating patients with previously untreated CD30+ advanced classic Hodgkin lymphoma (cHL). |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Brigatinib |
Brigatinib tablet (30 mg, 90 mg, 180 mg) |
Alunbrig |
Treatment of locally advanced or metastatic ALK mutation-positive non-small-cell lung cancer. |
MAF |
$ 2,000 |
$ 600 |
10 |
Others |
Bromocriptine |
Bromocriptine tablet (2.5 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others
| Busulfan
| Busulfan injection (60 mg)
| - | For cancer treatment.
| SDL | $ 200 | $ 600 | 1 |
Others |
Busulfan |
Busulfan tablet (2 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Prostate cancer |
Cabazitaxel |
Cabazitaxel injection (60 mg/1.5 mL) |
Jevtana |
Cabazitaxel in combination with prednisolone: for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with a docetaxel-containing regimen. Androgen deprivation therapy (ADT) should be continued. |
No subsidy |
$ 1,400 |
$ 600 |
7 |
Neuroendocrine |
Cabergoline |
Cabergoline tablet (0.5 mg) |
Dostinex |
As a 2nd line agent for the management of hyperprolactinaemia in patients who have failed to respond or who are unable to tolerate bromocriptine. |
MAF |
$ 200 |
$ 600 |
1 |
Liver cancer |
Cabozantinib |
Cabozantinib tablet (20 mg, 40 mg, 60 mg) |
Cabometyx |
Treatment of advanced unresectable hepatocellular carcinoma in patients with disease progression after 1 or more prior lines of systemic therapy, and who have adequate liver function as assessed by the Child-Pugh scoring system. |
MAF |
$ 1,800 |
$ 600 |
9 |
Renal cancer |
Cabozantinib |
Cabozantinib tablet (20 mg, 40 mg, 60 mg) |
Cabometyx |
For previously treated advanced renal cell carcinoma. |
MAF |
$ 1,800 |
$ 600 |
9 |
Renal cancer |
Cabozantinib |
Cabozantinib tablet (20 mg, 40 mg, 60 mg) |
Cabometyx |
For untreated intermediate- or poor-risk advanced renal cell carcinoma. |
MAF |
$ 1,800 |
$ 600 |
9 |
Others |
Capecitabine |
Capecitabine tablet (150 mg, 500 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Carboplatin |
Carboplatin vial (150 mg/15 mL, 450 mg/45 mL) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Multiple myeloma |
Carfilzomib |
Carfilzomib powder for solution for infusion (30 mg) |
Kyprolis |
Carfilzomib in combination with dexamethasone for patients with multiple myeloma who have received at least one prior therapy. |
MAF |
$ 2,000 |
$ 600 |
10 |
Multiple myeloma |
Carfilzomib |
Carfilzomib powder for solution for infusion (30 mg) |
Kyprolis |
Carfilzomib in combination with lenalidomide or thalidomide or cyclophosphamide, plus dexamethasone, for patients with multiple myeloma who have received at least one prior therapy. Treatment with carfilzomib should be stopped after 18 cycles, or earlier if disease progresses. |
MAF |
$ 2,000 |
$ 600 |
10 |
Others |
Carmustine |
Carmustine injection (100 mg) |
BiCNU |
For cancer treatment. |
SDL |
$ 2,000 |
$ 600 |
10 |
Others |
Ceritinib |
Ceritinib capsule (150 mg) |
Zykadia |
For cancer treatment. |
SDL |
$ 1,000 |
$ 600 |
5 |
Others |
Cetuximab |
Cetuximab solution for infusion (100 mg/20 mL) |
Erbitux |
For cancer treatment. |
SDL |
$ 1,000 |
$ 600 |
5 |
Others |
Chlorambucil |
Chlorambucil tablet (2 mg) |
Leukeran |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Others |
Cisplatin |
Cisplatin injection (50 mg/50 mL, 100 mg/100 mL injection) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Leukaemia |
Cladribine |
Cladribine injection (10 mg/5 mL, 10 mg/10 mL) |
- |
Treatment of hairy cell leukaemia. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Lymphoma |
Copanlisib |
Copanlisib injection (60 mg) |
Aliqopa |
Treatment of adults with relapsed follicular lymphoma who have received at least two prior systemic therapies. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Crisantaspase |
Crisantaspase injection (10,000 IU) |
Erwinase |
For cancer treatment in patients who have developed hypersensitivity to E.coli-derived asparaginase. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Lung cancer |
Crizotinib |
Crizotinib capsule (200 mg, 250 mg) |
Xalkori |
Treatment of patients with locally advanced or metastatic ROS1 mutation-positive non-small-cell lung cancer. Patients must not have received prior treatment with other ROS1 inhibitors. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Lymphoma |
Crizotinib |
Crizotinib capsule (200 mg, 250 mg) |
Xalkori |
Paediatric patients 1 year of age and older and young adults with relapsed or refractory, systemic anaplastic large cell lymphoma that is ALK-positive. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Others |
Cyclophosphamide |
Cyclophosphamide vial (1 g) and tablet (50 mg) |
Endoxan |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Cyproterone |
Cyproterone tablet (50 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Cytarabine |
Cytarabine vial (1 g/10 mL) |
- |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Lung cancer |
Dabrafenib plus trametinib |
Dabrafenib capsule (50 mg, 75 mg) Trametinib tablet (0.5 mg, 2 mg) |
Tafinlar Mekinist |
Dabrafenib in combination with trametinib for the treatment of advanced non-small-cell lung cancer (NSCLC) in patients with a BRAF V600 mutation. |
MAF |
$ 3,800 |
$ 600 |
19 |
Skin cancer |
Dabrafenib plus trametinib |
Dabrafenib capsule (50 mg, 75 mg) Trametinib tablet (0.5 mg, 2 mg) |
Tafinlar Mekinist |
Dabrafenib in combination with trametinib for the treatment of advanced unresectable or metastatic malignant melanoma in patients with a BRAF V600 mutation. Patients must not have received prior treatment with a BRAF/MEK inhibitor for unresectable or metastatic melanoma. |
MAF |
$ 3,800 |
$ 600 |
19 |
Thyroid cancer |
Dabrafenib plus trametinib |
Dabrafenib capsule (50 mg, 75 mg) Trametinib tablet (0.5 mg, 2 mg) |
Tafinlar Mekinist |
Dabrafenib in combination with trametinib for treating locally advanced or metastatic anaplastic thyroid cancer in patients with a BRAF V600 mutation and with no satisfactory locoregional treatment options. |
MAF |
$ 3,800 |
$ 600 |
19 |
Skin cancer |
Dabrafenib plus trametinib |
Dabrafenib capsule (50 mg, 75 mg) Trametinib tablet (0.5 mg, 2 mg) |
Tafinlar Mekinist |
Dabrafenib in combination with trametinib for the adjuvant treatment of completely resected malignant melanoma in patients with BRAF V600 mutation-positive disease and lymph node involvement. Maximum duration of treatment: 12 months. |
No subsidy |
$ 3,800 |
$ 600 |
19 |
Others |
Dacarbazine |
Dacarbazine vial (200 mg) |
- |
For cancer treatment. |
SDL |
$ 600 |
$ 600 |
3 |
Others |
Dacomitinib |
Dacomitinib tablet (15 mg, 30 mg, 45 mg) |
Vizimpro |
For cancer treatment. |
SDL |
$ 600 |
$ 600 |
3 |
Others |
Dactinomycin |
Dactinomycin vial (500 mcg) |
- |
For cancer treatment. |
SDL |
$ 1,600 |
$ 600 |
8 |
Multiple myeloma |
Daratumumab |
Daratumumab concentrate for solution for infusion (100 mg/5 mL, 400 mg/20 mL) and SC solution for injection (1800 mg/15 mL) |
Darzalex |
Daratumumab in combination with bortezomib and dexamethasone for patients with multiple myeloma who have received at least one prior therapy. |
No subsidy |
$ 2,000 |
$ 600 |
10 |
Multiple myeloma |
Daratumumab |
Daratumumab concentrate for solution for infusion (100 mg/5 mL, 400 mg/20 mL) and SC solution for injection (1800 mg/15 mL) |
Darzalex |
Daratumumab in combination with bortezomib, thalidomide and dexamethasone for patients with newly diagnosed multiple myeloma who are eligible for an autologous stem cell transplant. |
No subsidy |
$ 2,000 |
$ 600 |
10 |
Multiple myeloma |
Daratumumab |
Daratumumab concentrate for solution for infusion (100 mg/5 mL, 400 mg/20 mL) and SC solution for injection (1800 mg/15 mL) |
Darzalex |
Daratumumab in combination with lenalidomide and dexamethasone for patients with multiple myeloma who have received at least one prior therapy. |
No subsidy |
$ 2,000 |
$ 600 |
10 |
Multiple myeloma |
Daratumumab |
Daratumumab concentrate for solution for infusion (100 mg/5 mL, 400 mg/20 mL) and SC solution for injection (1800 mg/15 mL) |
Darzalex |
Daratumumab in combination with lenalidomide and dexamethasone for patients with newly diagnosed multiple myeloma who are ineligible for an autologous stem cell transplant. |
No subsidy |
$ 2,000 |
$ 600 |
10 |
Others | Daratumumab | Daratumumab SC solution for injection (1800 mg/15 mL)
| Darzalex | Daratumumab in combination with bortezomib, cyclophosphamide and dexamethasone for patients with previously untreated light chain (AL) amyloidosis. Treatment with daratumumab should be continued until disease progression or for a maximum of 24 cycles.
| No subsidy
| $ 2,000
| $ 600
| 10
|
Prostate cancer |
Darolutamide |
Darolutamide tablet (300 mg) |
Nubeqa | In combination with androgen deprivation therapy (ADT) for treating patients with high-risk non-metastatic castration-resistant prostate cancer (nmCRPC). |
No subsidy |
$ 400 |
$ 600 |
2 |
Leukaemia |
Dasatinib |
Dasatinib tablet (20 mg, 50 mg, 70 mg) |
- |
Treatment of adults with treatment-resistant or treatment-intolerant chronic myeloid leukemia (CML) in chronic phase, accelerated phase, or myeloid or lymphoid blast phase or children with treatment-resistant or treatment-intolerant CML in chronic phase. |
MAF |
$ 1,200 |
$ 600 |
6 |
Leukaemia |
Dasatinib |
Dasatinib tablet (20 mg, 50 mg, 70 mg) |
- |
Treatment of newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukaemia in combination with chemotherapy. |
MAF |
$ 1,200 |
$ 600 |
6 |
Leukaemia |
Dasatinib |
Dasatinib tablet (20 mg, 50 mg, 70 mg) |
- |
Treatment of newly diagnosed Philadelphia chromosome-positive chronic myeloid leukaemia in chronic phase. |
MAF |
$ 1,200 |
$ 600 |
6 |
Leukaemia |
Dasatinib |
Dasatinib tablet (20 mg, 50 mg, 70 mg) |
- |
Treatment of patients with Philadelphia chromosome positive acute lymphoblastic leukaemia with resistance or intolerance to prior treatment with imatinib. |
MAF |
$ 1,200 |
$ 600 |
6 |
Others |
Daunorubicin |
Daunorubicin vial (20 mg ) |
- |
For cancer treatment. |
SDL |
$ 600 |
$ 600 |
3 |
Others |
Decitabine |
Decitabine 50mg injection |
|
For cancer treatment. |
No subsidy |
$ 600 |
$ 600 |
3 |
Prostate cancer |
Degarelix |
Degarelix powder and solvent for solution for injection (80 mg, 120 mg) |
Firmagon |
Treatment of patients with advanced hormone-dependent prostate cancer. |
MAF |
$ 200 |
$ 600 |
1 |
Others |
Desmopressin |
Desmopressin nasal spray (10 mcg/dose) |
Minirin Presinex |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Desmopressin |
Desmopressin tablet (0.1 mg, 0.2 mg) |
Minirin |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Others |
Dexamethasone |
Dexamethasone injection (4 mg) and tablet (0.5mg, 4 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Neuroendocrine | Dinutuximab beta | Dinutuximab beta concentrate for solution for infusion (20 mg/4.5 mL)
| - | Treatment of high-risk neuroblastoma in patients who have previously received induction chemotherapy and achieved at least a partial response.
| No subsidy | $ 3,000 | $ 600 | 15 |
Neuroendocrine
| Dinutuximab beta
| Dinutuximab beta concentrate for solution for infusion (20 mg/4.5 mL)
| - | Treatment of patients with history of relapsed or refractory neuroblastoma, with or without residual disease.
| No subsidy
| $ 3,000
| $ 600 | 15 |
Others |
Docetaxel |
Docetaxel vial (20 mg , 80 mg, 160 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Endometrial cancer | Dostarlimab | Dostarlimab vial (500 mg) | Jemperli | Monotherapy for the treatment of patients with recurrent or advanced mismatch repair deficient (dMMR)/ microsatellite instability-high (MSI-H) endometrial cancer that has progressed on or following prior treatment with a platinum-containing regimen. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for recurrent or advanced MSI-H or dMMR endometrial cancer. | No subsidy | $ 1,800 | $ 600 | 9 |
Others |
Doxorubicin |
Doxorubicin vial (50 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Lung cancer |
Durvalumab |
Durvalumab concentrate for solution for infusion (120 mg/2.4 mL, 500 mg/10 mL) |
Imfinzi |
Consolidation treatment of patients with locally advanced, unresectable NSCLC whose disease has not progressed following platinum-based chemo-radiation therapy. Treatment should be continued until disease progression or unacceptable toxicity or for a maximum of 12 months. Durvalumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Durvalumab |
Durvalumab concentrate for solution for infusion (120 mg/2.4 mL, 500 mg/10 mL) |
Imfinzi |
Durvalumab in combination with a platinum agent and etoposide, for untreated extensive-stage small-cell lung cancer. |
MAF |
$ 1,800 |
$ 600 |
9 |
Upper gastrointestinal cancer | Durvalumab
| Durvalumab concentrate for solution for infusion (120 mg/2.4 mL, 500 mg/10 mL)
| Imfinzi
| In combination with cisplatin and gemcitabine for the treatment of patients with locally advanced or metastatic biliary tract cancer.
| No subsidy | $ 1,800
| $ 600
| 9 |
Colorectal cancer | Encorafenib | Encorafenib capsule (75 mg)
| Braftovi | Encorafenib in combination with cetuximab for the treatment of patients with metastatic colorectal cancer with a BRAF V600E mutation, who have received prior systemic therapy.
| No subsidy | $ 1800 | $ 600 | 9 |
Bladder cancer | Enfortumab vedotin | Enfortumab vedotin powder for concentrate for solution for infusion (20 mg, 30 mg) | Padcev
| Treatment of patients with locally advanced or metastatic urothelial cancer who have previously received a PD-1 or PD-L1 inhibitor, and a platinum-containing chemotherapy in the neoadjuvant/adjuvant, locally advanced or metastatic setting.
| No subsidy | $ 1,800 | $ 600 | 9 |
Lung cancer |
Entrectinib |
Entrectinib capsule (100 mg, 200 mg) |
Rozlytrek |
Treatment of patients with locally advanced or metastatic ROS1 mutation-positive non-small-cell lung cancer. Patients must not have received prior treatment with other ROS1 inhibitors. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Tumour agnostic |
Entrectinib |
Entrectinib capsule (100 mg, 200 mg) |
Rozlytrek |
Treatment of patients with solid tumours that: - have a NTRK gene fusion without a known acquired resistance mutation, - are metastatic or where surgical resection is likely to result in severe morbidity, and - have no satisfactory alternative treatments or that have progressed following treatment. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Prostate cancer |
Enzalutamide |
Enzalutamide capsule (40 mg) |
Xtandi | In combination with androgen deprivation therapy (ADT) for treating patients with high-risk non-metastatic castration-resistant prostate cancer (nmCRPC). |
MAF |
$ 400 |
$ 600 |
2 |
Prostate cancer |
Enzalutamide |
Enzalutamide capsule (40 mg) |
Xtandi | In combination with androgen deprivation therapy (ADT) for treating patients with metastatic castration-resistant prostate cancer (mCRPC). |
MAF |
$ 400 |
$ 600 |
2 |
Prostate cancer |
Enzalutamide |
Enzalutamide capsule (40 mg) |
Xtandi | In combination with androgen deprivation therapy (ADT) for treating patients with metastatic hormone-sensitive prostate cancer (mHSPC). |
MAF |
$ 400 |
$ 600 |
2 |
Others |
Epirubicin |
Epirubicin injection (50 mg/25 mL) |
- |
For cancer treatment. |
SDL |
$ 800 |
$ 600 |
4 |
Bladder cancer |
Erdafitinib |
Erdafitinib tablet (3 mg, 4 mg, 5 mg) |
Balversa |
Treatment of patients with locally advanced or metastatic urothelial carcinoma, whose tumours have susceptible FGFR3 genetic alterations, and who have disease progression during or following at least one line of prior chemotherapy including within 12 months of neoadjuvant or adjuvant chemotherapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Breast cancer |
Eribulin mesylate |
Eribulin mesylate solution for injection (1 mg/2 mL) |
Halaven |
Treatment of locally advanced or metastatic breast cancer in patients whose disease has progressed after at least two chemotherapy regimens for advanced disease. |
MAF |
$ 1,200 |
$ 600 |
6 |
Sarcoma |
Eribulin mesylate |
Eribulin mesylate solution for injection (1 mg/2 mL) |
Halaven |
Treatment of patients with unresectable liposarcoma who have received prior anthracycline containing therapy (unless unsuitable) for advanced or metastatic disease. |
MAF |
$ 1,200 |
$ 600 |
6 |
Others |
Erlotinib |
Erlotinib tablet (100 mg, 150 mg) |
- |
For cancer treatment. |
SDL
|
$ 200 |
$ 600 |
1 |
Others |
Etoposide |
Etoposide capsule (50 mg) |
- |
For cancer treatment. |
SDL |
$ 600 |
$ 600 |
3 |
Others |
Etoposide |
Etoposide vial (100 mg/5 mL) |
- |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
1 |
Neuroendocrine |
Everolimus |
Everolimus tablet (2.5 mg, 5 mg, 10 mg) |
Afinitor |
Treatment of unresectable or metastatic, well-differentiated, non-functional neuroendocrine tumours of gastrointestinal or lung origin and with progressive disease. |
MAF |
$ 1,200 |
$ 600 |
6 |
Neuroendocrine |
Everolimus |
Everolimus tablet (2.5 mg, 5 mg, 10 mg) |
Afinitor |
Treatment of unresectable, locally advanced or metastatic neuroendocrine tumours of pancreatic origin and with progressive disease. |
MAF |
$ 1,200 |
$ 600 |
6 |
Breast cancer |
Everolimus |
Everolimus tablet (2.5 mg, 5 mg, 10 mg) |
Afinitor |
Everolimus in combination with exemestane for HR positive, HER2/neu negative advanced breast cancer, in postmenopausal women without symptomatic visceral disease after recurrence or progression following a non-steroidal aromatase inhibitor. |
No subsidy |
$ 1,200 |
$ 600 |
6 |
Renal cancer |
Everolimus |
Everolimus tablet (2.5 mg, 5 mg, 10 mg) |
Afinitor |
For previously treated advanced renal cell carcinoma. |
No subsidy |
$ 1,200 |
$ 600 |
6 |
Others |
Exemestane |
Exemestane tablet (25 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Myeloproliferative neoplasms | Fedratinib | Fedratinib capsule (100 mg) | Inrebic | For the treatment of splenomegaly and/or disease related symptoms in patients with intermediate-2 or high-risk primary myelofibrosis, post-polycythemia vera myelofibrosis or post-essential thrombocythemia myelofibrosis, including patients who have been previously exposed to ruxolitinib.
| MAF | $ 2,000 | $ 600 | 10 |
Others |
Fludarabine |
Fludarabine injection (50 mg) |
- |
For cancer treatment. |
SDL |
$ 600 |
$ 600 |
3 |
Skin cancer | Fluorouracil | Fluorouracil cream (5%) | - | Treatment of actinic keratosis, Bowen’s disease, or superficial basal cell carcinoma.
| No subsidy | $ 200 | $ 600 | 1 |
Others |
Fluorouracil |
Fluorouracil vial (500 mg/10 mL, 1g/20 mL, 5g/100 mL) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Prostate cancer |
Flutamide |
Flutamide tablet (250 mg) |
- |
Flutamide in combination with luteinising hormone-releasing hormone (LHRH) agonists for previously untreated advanced prostatic carcinoma. |
No subsidy |
$ 200 |
$ 600 |
1 |
Others |
Folinic acid |
Folinic acid vial (50 mg/5 mL, 300 mg/30 mL) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Fulvestrant |
Fulvestrant solution for injection in pre-filled syringe (250 mg/5 mL) |
- |
For cancer treatment. |
SDL
|
$ 200 |
$ 600 |
1 |
Others |
Gefitinib |
Gefitinib tablet (250 mg) |
- |
For cancer treatment. |
SDL
|
$ 200 |
$ 600 |
1 |
Others |
Gemcitabine |
Gemcitabine vial (200 mg, 1 g, 2 g) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Leukaemia |
Gemtuzumab ozogamicin |
Gemtuzumab ozogamicin powder for concentrate for solution for infusion vial (5 mg) |
Mylotarg |
In combination with daunorubicin and cytarabine for patients with previously untreated de novo CD33-positive acute myeloid leukaemia (AML), if they: • do not have acute promyelocytic leukaemia, • only start induction therapy while waiting for cytogenetic test results or after confirming favourable, intermediate or unknown (due to inconclusive test results) cytogenetic risk, and • start consolidation therapy after confirming favourable, intermediate, or unknown cytogenetic risk. |
MAF |
$ 3,200 |
$ 600 |
16 |
Leukaemia |
Gilteritinib |
Gilteritinib fumarate tablet (40 mg) |
Xospata |
Treatment of FLT-3 mutation positive relapsed / refractory acute myeloid leukaemia (AML). Gilteritinib is not recommended as maintenance therapy for patients after HSCT. |
MAF |
$ 9,200 |
$ 1,200 |
46 |
Breast cancer |
Goserelin acetate |
Goserelin acetate depot injection (3.6 mg, 10.8 mg) |
Zoladex |
Treatment of breast cancer where hormone therapy is specified. |
MAF |
$ 200 |
$ 600 |
1 |
Prostate cancer |
Goserelin acetate |
Goserelin acetate depot injection (3.6 mg, 10.8 mg) |
Zoladex |
Treatment of locally advanced or metastatic prostate cancer. |
MAF |
$ 200 |
$ 600 |
1 |
Others |
Hydroxyurea |
Hydroxyurea capsule (500 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Leukaemia |
Ibrutinib plus rituximab |
Ibrutinib capsule (140 mg), and tablet (140 mg, 280 mg, 420 mg tablet)
Rituximab concentrate for infusion (100 mg/10 mL, 500 mg/50 mL) |
Imbruvica
MabThera Truxima Rixathon |
Ibrutinib in combination with rituximab for previously untreated chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Leukaemia
| Ibrutinib plus obinutuzumab
| Ibrutinib capsule (140 mg), and tablet (140 mg, 280 mg, 420 mg tablet)
Obinutuzumab concentrate for solution for infusion (1000 mg/40 mL)
| Imbruvica
Gazyva
| Ibrutinib in combination with obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). | No subsidy | $ 3,000 | $ 600 | 15 |
Leukaemia |
Ibrutinib |
Ibrutinib capsule (140 mg), and tablet (140 mg, 280 mg, 420 mg tablet) |
Imbruvica |
Monotherapy for patients with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) who have received at least one prior therapy. |
No subsidy |
$ 2,000 |
$ 600 |
10 |
Leukaemia |
Ibrutinib |
Ibrutinib capsule (140 mg), and tablet (140 mg, 280 mg, 420 mg tablet) |
Imbruvica |
Monotherapy for patients with previously untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who are unsuitable for fludarabine-based therapy. |
No subsidy |
$ 2,000 |
$ 600 |
10 |
Lymphoma |
Ibrutinib |
Ibrutinib capsule (140 mg), and tablet (140 mg, 280 mg, 420 mg tablet) |
Imbruvica |
Monotherapy for the treatment of Waldenstrom’s Macroglobulinaemia. |
No subsidy |
$ 2,000 |
$ 600 |
10 |
Lymphoma | Ibrutinib plus rituximab
| Ibrutinib capsule (140 mg), and tablet (140 mg, 280 mg, 420 mg tablet)
Rituximab concentrate for infusion (100 mg/10 mL, 500 mg/50 mL)
| Imbruvica
MabThera Truxima Rixathon
| Ibrutinib in combination with rituximab, for the treatment of Waldenstrom’s Macroglobulinaemia.
| No subsidy
| $ 2,000
| $ 600
| 10
|
Lymphoma |
Ibrutinib |
Ibrutinib capsule (140 mg), and tablet (140 mg, 280 mg, 560 mg) |
Imbruvica |
Treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. |
No subsidy |
$ 2,000 |
$ 600 |
10 |
Leukaemia |
Idarubicin |
Idarubicin solution for injection (5 mg/5 mL, 10 mg/10 mL) |
Zavedos CS |
Treatment of acute myeloid leukaemia (AML) in patients for remission induction. |
No subsidy |
$ 400 |
$ 600 |
2 |
Lymphoma |
Idelalisib |
Idelalisib tablet (150 mg) |
Zydelig |
Treatment of adults with relapsed follicular lymphoma who have received at least two prior systemic therapies. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Others |
Ifosfamide |
Ifosfamide infusion (1 g) |
Holoxan |
For cancer treatment. |
SDL |
$ 2,400 |
$ 600 |
12 |
Others |
Imatinib |
Imatinib tablet and capsule (100 mg, 400 mg) |
- |
For cancer treatment. |
SDL
|
$ 200 |
$ 600 |
1 |
Skin cancer |
Imiquimod |
Imiquimod cream (5%) |
Aldara |
Treatment of actinic keratosis or superficial basal cell carcinoma. |
No subsidy |
$ 200 |
$ 600 |
1 |
Leukaemia |
Inotuzumab ozogamicin |
Inotuzumab ozogamicin powder for concentrate for solution for infusion (1 mg per vial) |
Besponsa |
Treatment of patients with relapsed or refractory CD22 positive B-precursor acute lymphoblastic leukemia (ALL) for: - up to a maximum of three cycles for induction in a lifetime, and - up to three additional cycles for consolidation in a lifetime in patients who achieve a complete response after induction Patients with Philadelphia chromosome positive disease must have previously received a tyrosine kinase inhibitor before receiving inotuzumab. Complete response is defined as a patient who: a) has 5% or less bone marrow blasts; and b) has no evidence of disease; and c) has platelet count of more than 50,000 per microlitre; and d) has absolute neutrophil count of more than 500 per microlitre. |
MAF |
$ 9,600 |
$ 1,200 |
48 |
Others |
Interferon alfa 2a |
Interferon alfa 2a injection (3 million iu/ 0.5 mL) |
- |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Others |
Irinotecan hydrochloride |
Irinotecan hydrochloride trihydrate concentrate for infusion (100 mg/5 mL) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Multiple myeloma | Isatuximab plus pomalidomide | Isatuximab concentrate for solution for infusion (100 mg/5 mL and 500 mg/25 mL)
Pomalidomide capsule (1 mg, 2 mg, 3 mg, 4 mg)
| Sarclisa
Pomalyst | Isatuximab in combination with pomalidomide and dexamethasone for the treatment of patients with relapsed and refractory multiple myeloma who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on the last therapy.
| No subsidy
| $ 2,000
| $ 600
| 10
|
Multiple myeloma
| Isatuximab plus carfilzomib | Isatuximab concentrate for solution for infusion (100 mg/5 mL and 500 mg/25 mL)
Carfilzomib powder for solution for infusion (30 mg) | Sarclisa
Kyprolis
| Isatuximab in combination with carfilzomib and dexamethasone for the treatment of patients with relapsed or refractory multiple myeloma who have received one to three prior therapies.
| No subsidy
| $ 2,000
| $ 600
| 10
|
Multiple myeloma |
Ixazomib |
Ixazomib capsule (3 mg, 4 mg) |
Ninlaro |
Ixazomib in combination with lenalidomide and dexamethasone for patients with multiple myeloma who have received at least one prior therapy. |
MAF |
$ 2,000 |
$ 600 |
10 |
Neuroendocrine |
Lanreotide |
Lanreotide prolonged release (PR) injection (60 mg, 90 mg, 120 mg) |
Somatuline Autogel |
For the reduction of symptoms associated with carcinoid syndrome. |
MAF |
$ 600 |
$ 600 |
3 |
Neuroendocrine |
Lanreotide |
Lanreotide prolonged release (PR) injection (60 mg, 90 mg, 120 mg) |
Somatuline Autogel |
Treatment of neuroendocrine tumours of gastrointestinal or pancreatic origin. |
MAF |
$ 600 |
$ 600 |
3 |
Neuroendocrine
| Lanreotide
| Lanreotide prolonged release (PR) injection (60 mg, 90 mg, 120 mg)
| Somatuline Autogel
| Treatment of acromegaly in patients with abnormal levels of Growth Hormone (GH) and/or Insulin-like Growth Factor-1 (IGF-1) after surgery and/or radiotherapy or in patients who require medical treatment.
| MAF | $ 600
| $ 600
| 3
|
Neuroendocrine
| Lanreotide
| Lanreotide prolonged release (PR) injection (60 mg, 90 mg, 120 mg)
| Somatuline Autogel
| For the improvement of symptoms associated with acromegaly.
| MAF | $ 600
| $ 600
| 3
|
Breast cancer |
Lapatinib |
Lapatinib tablet (250 mg) |
Tykerb |
Lapatinib in combination with an aromatase inhibitor for postmenopausal women with HR positive, HER2 positive metastatic breast cancer. |
MAF |
$ 800 |
$ 600 |
4 |
Breast cancer |
Lapatinib |
Lapatinib tablet (250 mg) |
Tykerb |
Lapatinib in combination with capecitabine for HER2 positive, advanced or metastatic breast cancer in patients whose disease has progressed after treatment with an anthracycline and, a taxane, and on prior trastuzumab therapy in the metastatic setting. |
MAF |
$ 800 |
$ 600 |
4 |
Tumour agnostic |
Larotrectinib |
Larotrectinib capsule (25 mg, 100 mg) and oral solution (2 g/100 mL, 1g /50 mL (2 x 50 mL)) |
Vitrakvi |
Treatment of patients with solid tumours that: - have a NTRK gene fusion without a known acquired resistance mutation, - are metastatic or where surgical resection is likely to result in severe morbidity, and - have no satisfactory alternative treatments or that have progressed following treatment. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Others |
L-asparaginase |
L-asparaginase injection (10,000 IU) |
- |
For cancer treatment. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Others |
Lenalidomide |
Lenalidomide capsule (5 mg, 10 mg, 15 mg, 25 mg) |
- |
For cancer treatment. |
SDL
|
$ 1,400 |
$ 600 |
7 |
Liver cancer |
Lenvatinib |
Lenvatinib capsule (4 mg, 10 mg) |
Lenvima |
Treatment of advanced unresectable hepatocellular carcinoma in patients with adequate liver function as assessed by the Child-Pugh scoring system, when used according to HSA-recommended dosing regimens. |
MAF |
$ 1,200 |
$ 600 |
6 |
Thyroid cancer |
Lenvatinib |
Lenvatinib capsule (4 mg, 10 mg) |
Lenvima |
Treatment of locally advanced or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer. |
MAF |
$ 1,200 |
$ 600 |
6 |
Renal cancer |
Lenvatinib plus everolimus |
Lenvatinib capsule (4 mg, 10 mg)
Everolimus tablet (2.5 mg, 5 mg, 10 mg) |
Lenvima
Afinitor |
Lenvatinib in combination with everolimus for previously treated advanced renal cell carcinoma. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Others |
Letrozole |
Letrozole tablet (2.5 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Breast cancer |
Leuprorelin acetate |
Leuprorelin acetate depot injection (3.75 mg, 11.25 mg) |
Lucrin |
Treatment of breast cancer where hormone therapy is specified. |
MAF |
$ 200 |
$ 600 |
1 |
Prostate cancer |
Leuprorelin acetate |
Leuprorelin acetate depot injection (3.75 mg, 11.25 mg, 30 mg), powder and solvent for solution for injection (7.5 mg 22.5 mg, 45 mg) |
Lucrin Eligard |
Treatment of locally advanced or metastatic prostate cancer. |
MAF |
$ 200 |
$ 600 |
1 |
Others |
Liposomal doxorubicin |
Doxorubicin hydrochloride (pegylated liposome) concentrate for infusion (20 mg/10 mL) |
- |
For cancer treatment. |
SDL
|
$ 1,400 |
$ 600 |
7 |
Pancreatic cancer |
Liposomal irinotecan |
Pegylated liposomal irinotecan concentrate for dispersion for infusion (43 mg/10 mL) |
Onivyde |
Liposomal irinotecan in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. |
No subsidy |
$ 1,000 |
$ 600 |
5 |
Others |
Lomustine |
Lomustine capsule (10 mg, 40 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Lung cancer |
Lorlatinib |
Lorlatinib tablet (25 mg, 100 mg) |
Lorviqua |
Treatment of locally advanced or metastatic ALK mutation-positive non-small-cell lung cancer. |
MAF |
$ 2,000 |
$ 600 |
10 |
Lung cancer | Lurbinectedin
| Lurbinectedin powder for solution for infusion (4 mg)
| Zepzelca | Treatment of patients with metastatic small cell lung cancer (SCLC) who have progressed after prior platinum-containing therapy.
| No subsidy | $ 1800 | $ 600 | 9 |
Prostate cancer |
Lutetium PSMA |
Lutetium PSMA |
- |
Treatment of patients with metastatic castration resistant prostate cancer (mCRPC) previously treated with a docetaxel-containing regimen. |
No subsidy |
$ 1,400 |
$ 600 |
7 |
Neuroendocrine |
Lutetium-177 peptide |
Lutetium-177 (177-Lu) peptide |
- |
Treatment of unresectable or metastatic, progressive, well differentiated (G1 and G2), somatostatin receptor-positive gastro-entero-pancreatic neuroendocrine tumours (NETs), including foregut, midgut, and hindgut NETs. |
No subsidy |
$ 1,200 |
$ 600 |
6 |
Others |
Megestrol |
Megestrol tablet (40 mg, 160 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Melphalan |
Melphalan injection (50 mg) |
Alkeran |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Others |
Melphalan |
Melphalan tablet (2 mg) |
Alkeran |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Mercaptopurine |
Mercaptopurine tablet (50 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Mercaptopurine |
Mercaptopurine oral suspension (2000 mg/100 mL) |
- |
For cancer treatment. |
No subsidy |
$ 1,000 |
$ 600 |
5 |
Thyroid cancer |
Meta-iodobenzylguanidine |
Meta-iodobenzylguanidine [I-131] injection for therapeutic use (185 to 740 MBq/mL) |
- |
Radiation therapy of tumours arising from cells originating embryologically from the neural crest, pheochromocytomas, neuroblastomas, carcinoids and medullary carcinomas of the thyroid gland. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Others |
Methotrexate |
Methotrexate tablet (2.5 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Methotrexate |
Methotrexate injection (50 mg/2 mL, 1g/10 mL) |
- |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Others |
Methylprednisolone |
Methylprednisolone injection (500 mg, 1 g) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Leukaemia |
Midostaurin |
Midostaurin capsule (25 mg) |
Rydapt |
Treatment of FLT-3-mutation positive acute myeloid leukaemia (AML) in combination with standard intensive induction and consolidation chemotherapy. Standard induction chemotherapy must include cytarabine and an anthracycline. Midostaurin is not recommended for maintenance therapy. |
MAF |
$ 2,400 |
$ 600 |
12 |
Leukaemia |
Midostaurin |
Midostaurin capsule (25 mg) |
Rydapt |
Treatment of aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN) or mast cell leukaemia (MCL). |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Others |
Mitomycin |
Mitomycin injection (2 mg, 10 mg) |
- |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Neuroendocrine |
Mitotane |
Mitotane tablet (500 mg) |
- |
For symptomatic treatment of advanced (unresectable, metastatic or relapsed) adrenal cortical carcinoma. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Others |
Mitoxantrone |
Mitoxantrone vial (20 mg/10 mL) |
- |
For cancer treatment. |
SDL |
$ 1,000 |
$ 600 |
5 |
Breast cancer |
Nab-paclitaxel |
Paclitaxel - albumin bound nanoparticles injectable suspension (100 mg) |
Abraxane |
Monotherapy for metastatic breast cancer in patients who have failed first-line treatment for metastatic disease and for whom standard, anthracycline containing therapy is not indicated. |
MAF |
$ 1,000 |
$ 600 |
5 |
Lung cancer |
Nab-paclitaxel |
Paclitaxel - albumin bound nanoparticles injectable suspension (100 mg) |
Abraxane |
Nab-paclitaxel in combination with carboplatin, for previously untreated locally advanced or metastatic non-small cell lung cancer in patients who are not candidates for curative surgery or radiation therapy. |
MAF |
$ 1,000 |
$ 600 |
5 |
Pancreatic cancer |
Nab-paclitaxel |
Paclitaxel - albumin bound nanoparticles injectable suspension (100 mg) |
Abraxane |
Nab-paclitaxel in combination with gemcitabine, for treatment of locally advanced or metastatic adenocarcinoma of the pancreas. |
MAF |
$ 1,000 |
$ 600 |
5 |
Others |
Nab-paclitaxel |
Paclitaxel - albumin bound nanoparticles injectable suspension (100 mg) |
Abraxane |
For cancer treatment in patients who are intolerant to paclitaxel. |
MAF |
$ 1,000 |
$ 600 |
5 |
Leukaemia |
Nelarabine |
Nelarabine injection (250 mg/50 mL) |
- |
Treatment of T-cell acute lymphoblastic leukaemia and T-cell lymphoblastic lymphoma that has not responded to or has relapsed following treatment with at least 2 chemotherapy regimens. |
No subsidy |
$ 1,000 |
$ 600 |
5 |
Breast cancer | Neratinib | Neratinib tablet (40 mg) | Nerlynx | In combination with capecitabine for treating patients with advanced or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting. | No subsidy | $ 800 | $ 600 | 4 |
Breast cancer | Neratinib | Neratinib tablet (40 mg)
| Nerlynx
| Extended adjuvant treatment of patients with early stage HER2-overexpressed/ amplified breast cancer, to follow adjuvant trastuzumab-based therapy. Treatment of neratinib should be initiated within 1 year after completion of trastuzumab therapy. | No subsidy | $ 800 | $ 600 | 4 |
Leukaemia |
Nilotinib |
Nilotinib capsule (50 mg, 150 mg, 200 mg) |
Tasigna |
Treatment of adults with treatment-resistant or treatment-intolerant chronic myeloid leukaemia (CML) in chronic phase or accelerated phase; or children with treatment-resistant or treatment-intolerant CML in chronic phase. |
MAF |
$ 1,200 |
$ 600 |
6 |
Leukaemia |
Nilotinib |
Nilotinib capsule (50 mg, 150 mg, 200 mg) |
Tasigna |
Treatment of newly diagnosed Philadelphia chromosome-positive (Ph+) chronic myeloid leukaemia (CML) in chronic phase. |
MAF |
$ 1,200 |
$ 600 |
6 |
Ovarian cancer | Niraparib | Niraparib tablet (100 mg) | Zejula | Maintenance monotherapy for patients with advanced epithelial high-grade ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to first-line platinum- based chemotherapy and whose cancer is associated with BRCA mutation and/or homologous recombination deficiency (HRD) positive status. Treatment should be continued until disease progression or unacceptable toxicity or a maximum of 36 months.
| MAF | $ 1,600 | $ 600 | 8 |
Ovarian cancer |
Niraparib |
Niraparib tablet (100 mg) |
Zejula |
Maintenance monotherapy for patients with advanced epithelial high-grade ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to first-line platinum-based chemotherapy. Treatment should be continued until disease progression or unacceptable toxicity or a maximum of 36 months. |
No subsidy |
$ 1,600 |
$ 600 |
8 |
Ovarian cancer |
Niraparib |
Niraparib tablet (100 mg) |
Zejula |
Maintenance monotherapy for patients with platinum-sensitive relapsed BRCA-mutated high-grade serous epithelial ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy. Patients must not have received prior treatment with a PARP inhibitor for ovarian cancer. Treatment should be continued until disease progression or unacceptable toxicity. |
No subsidy |
$ 1,600 |
$ 600 |
8 |
Head and neck cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
For patients with recurrent or metastatic squamous cell cancer of the head and neck whose disease progressed within six months of starting platinum-based chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for this condition in the recurrent or metastatic setting. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
Treatment of patients with metastatic non-small cell lung cancer (NSCLC) who have disease progression during or following platinum-containing chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for metastatic NSCLC. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
Treatment of patients with relapsed or refractory classical Hodgkin lymphoma (cHL) after an autologous stem cell transplant (ASCT) and treatment with brentuximab vedotin. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for this condition in the relapsed or refractory setting. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Renal cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
For previously treated advanced renal cell carcinoma (RCC). Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for advanced RCC. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Renal cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
For intermediate- or poor-risk advanced renal cell carcinoma, following induction treatment with nivolumab in combination with ipilimumab. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Skin cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
Adjuvant treatment of completely resected malignant melanoma in patients with lymph node involvement. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. Maximum duration of treatment: 12 months. |
MAF |
$ 1,800 |
$ 600 |
9 |
Skin cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
Monotherapy for advanced unresectable or metastatic malignant melanoma. Patients must not have received prior treatment with a PD-1 inhibitor or ipilimumab for advanced unresectable or metastatic malignant melanoma. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Skin cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL) |
Opdivo |
Treatment of advanced unresectable or metastatic malignant melanoma, following induction treatment with nivolumab in combination with ipilimumab. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Upper gastrointestinal cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
Treatment of patients with unresectable locally advanced or recurrent gastric or gastroesophageal junction (GEJ) adenocarcinoma after 2 or more prior systemic therapies. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for unresectable locally advanced or recurrent gastric or GEJ cancer. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
MAF |
$ 1,800 |
$ 600 |
9 |
Upper gastrointestinal cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL) |
Opdivo |
Adjuvant treatment of completely resected oesophageal or gastroesophageal junction cancer with residual pathologic disease in patients who have received neoadjuvant chemoradiotherapy. Maximum treatment duration: 12 months. |
MAF |
$ 1,800 |
$ 600 |
9 |
Upper gastrointestinal cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL) |
Opdivo |
Nivolumab in combination with fluoropyrimidine and platinum-based chemotherapy for untreated, unresectable advanced or metastatic HER2 negative gastric cancer, gastroesophageal junction cancer or oesophageal adenocarcinoma. Treatment with nivolumab should be stopped at 2 years, or earlier if disease progresses. |
MAF |
$ 1,800 |
$ 600 |
9 |
Upper gastrointestinal cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL) |
Opdivo |
Treatment of unresectable advanced, recurrent or metastatic oesophageal squamous cell carcinoma after prior fluoropyrimidine- and platinum-based combination chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for this condition in the unresectable advanced, recurrent or metastatic setting. |
MAF |
$ 1,800 |
$ 600 |
9 |
Bladder cancer | Nivolumab | Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL)
| Opdivo | Adjuvant treatment of patients with muscle invasive urothelial carcinoma (MIUC) with tumour cell PD-L1 expression ≥1%, who are at high risk of recurrence after undergoing radical resection of MIUC, and only if adjuvant treatment with platinum-based chemotherapy is unsuitable. Maximum duration of treatment: 12 months.
| No subsidy | $ 1,800
| $ 600
| 9 |
Bladder cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
Treatment of patients with locally advanced or metastatic urothelial carcinoma (UC) after receiving platinum-containing chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for locally advanced or metastatic UC. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Colorectal cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
Treatment of unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer (CRC) that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for unresectable or metastatic MSI-H or dMMR CRC. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Liver cancer |
Nivolumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) |
Opdivo |
Treatment of advanced unresectable hepatocellular carcinoma (HCC) in patients with disease progression after 1 or more prior lines of systemic therapy, and who have adequate liver function as assessed by the Child-Pugh scoring system. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for advanced unresectable HCC. Nivolumab should be given as a weight-based dose up to a maximum of 240 mg every two weeks or 480 mg every four weeks. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Lung cancer | Nivolumab | Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL)
| Opdivo | Nivolumab in combination with platinum-doublet chemotherapy for neoadjuvant treatment of resectable (tumours ≥4 cm or node positive) non-small cell lung cancer. Maximum duration of treatment: 3 cycles.
| No subsidy
| $ 1,800
| $ 600
| 9 |
Renal cancer |
Nivolumab plus cabozantinib |
Nivolumab concentrate for solution for infusion (40 mg/4mL, 100 mg/10mL)
Cabozantinib tablet (20 mg, 40 mg, 60 mg) |
Opdivo
Cabometyx |
Nivolumab in combination with cabozantinib for untreated advanced renal cell carcinoma. Treatment with nivolumab should be stopped at 2 years, or earlier if disease progresses. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Colorectal cancer |
Nivolumab plus ipilimumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL)
Ipilimumab injection concentrate (50 mg/10 mL) |
Opdivo
Yervoy |
Nivolumab in combination with ipilimumab for treatment of unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer (CRC) that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for unresectable or metastatic MSI-H or dMMR CRC. The doses of nivolumab and ipilimumab should not exceed: 3mg/kg nivolumab and 1mg/kg ipilimumab every 3 weeks for 4 doses, followed by nivolumab 240mg every 2 weeks or 480mg every 4 weeks as a single agent. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Liver cancer |
Nivolumab plus ipilimumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL)
Ipilimumab injection concentrate (50 mg/10 mL) |
Opdivo
Yervoy |
Nivolumab in combination with ipilimumab for treatment of advanced unresectable hepatocellular carcinoma (HCC) in patients with disease progression after 1 or more prior lines of systemic therapy, and who have adequate liver function as assessed by the Child-Pugh scoring system. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for advanced unresectable HCC. The doses of nivolumab and ipilimumab should not exceed: 1mg/kg nivolumab and 3mg/kg ipilimumab every 3 weeks for 4 doses, followed by nivolumab 240mg every 2 weeks or 480mg every 4 weeks as a single agent. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Nivolumab plus ipilimumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL)
Ipilimumab injection concentrate (50 mg/10 mL) |
Opdivo
Yervoy |
Nivolumab in combination with ipilimumab and 2 cycles of platinum-based chemotherapy, for untreated metastatic or recurrent non-small cell lung cancer (NSCLC) in patients with no EGFR or ALK genomic tumour mutations. Treatment with nivolumab and ipilimumab should be stopped at 2 years, or earlier if disease progresses. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Thoracic cancer | Nivolumab plus ipilimumab
| Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL)
Ipilimumab injection concentrate (50 mg/10 mL)
| Opdivo
Yervoy | Nivolumab in combination with ipilimumab for unresectable malignant pleural mesothelioma. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for this condition. The doses of nivolumab and ipilimumab should not exceed: 3mg/kg nivolumab every 2 weeks and 1mg/kg ipilimumab every 6 weeks. Treatment with nivolumab and ipilimumab should be stopped at 2 years, or earlier if disease progresses.
| No subsidy | $ 1,800
| $ 600
| 9 |
Upper gastrointestinal cancer | Nivolumab | Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL)
| Opdivo
| Nivolumab in combination with fluoropyrimidine and platinum-based chemotherapy for untreated, unresectable advanced, recurrent or metastatic oesophageal squamous cell carcinoma. Treatment with nivolumab should be stopped at 2 years, or earlier if disease progresses. | MAF
| $ 1,800
| $ 600
| 9
|
Upper gastrointestinal cancer
| Nivolumab plus ipilimumab
| Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL)
Ipilimumab injection concentrate (50 mg/10 mL)
| Opdivo
Yervoy
| Nivolumab in combination with ipilimumab for untreated, unresectable advanced, recurrent or metastatic oesophageal squamous cell carcinoma. The doses of nivolumab and ipilimumab should not exceed: 3mg/kg nivolumab every 2 weeks and 1mg/kg ipilimumab every 6 weeks. Treatment with nivolumab and ipilimumab should be stopped at 2 years, or earlier if disease progresses. | No subsidy
| $ 1,800
| $ 600
| 9
|
Renal cancer |
Nivolumab plus ipilimumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL) Ipilimumab injection concentrate (50 mg/10 mL) |
Opdivo Yervoy |
Nivolumab in combination with ipilimumab for untreated intermediate- or poor-risk advanced renal cell carcinoma. The doses of nivolumab and ipilimumab should not exceed: 3mg/kg nivolumab and 1mg/kg ipilimumab every 3 weeks for 4 doses. |
MAF |
$ 5,200 |
$ 600 |
26 |
Skin cancer |
Nivolumab plus ipilimumab |
Nivolumab concentrate for solution for infusion (40 mg/4 mL, 100 mg/10 mL, 240 mg/24 mL) Ipilimumab injection concentrate (50 mg/10 mL) |
Opdivo Yervoy |
Nivolumab in combination with ipilimumab for the treatment of advanced unresectable or metastatic malignant melanoma. The doses of nivolumab and ipilimumab should not exceed: 1mg/kg nivolumab and 3mg/kg ipilimumab every 3 weeks for 4 doses. |
MAF |
$ 7800 |
$ 1200 |
39 |
Lymphoma |
Obinutuzumab |
Obinutuzumab concentrate for solution for infusion (1000 mg/40 mL) |
Gazyva |
Obinutuzumab in combination with bendamustine, for the treatment of follicular lymphoma that has not responded to or progressed within 6 months after treatment with rituximab or a rituximab-containing regimen. Patients must not have received obinutuzumab for follicular lymphoma. Maintenance treatment with obinutuzumab should be stopped at 2 years, or earlier if disease progresses. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Obinutuzumab |
Obinutuzumab concentrate for solution for infusion (1000 mg/40 mL) |
Gazyva |
Obinutuzumab in combination with chemotherapy, for previously untreated stage II bulky, III or IV follicular lymphoma. Patients achieving at least a partial remission may continue to receive maintenance treatment with obinutuzumab monotherapy. Maintenance treatment with obinutuzumab should be stopped after 2 years, or earlier if disease progresses. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Others |
Octreotide |
Octreotide long-acting depot injection (20 mg, 30 mg) |
Sandostatin LAR |
For cancer treatment. |
SDL |
$ 600 |
$ 600 |
3 |
Breast cancer |
Olaparib |
Olaparib tablet (100 mg, 150 mg) |
Lynparza |
Treatment of germline BRCA-mutated, HER2 negative, locally advanced or metastatic breast cancer in patients previously treated with chemotherapy. |
MAF |
$ 1,600 |
$ 600 |
8 |
Breast cancer | Olaparib | Olaparib tablet (100 mg, 150 mg)
| Lynparza
| Adjuvant treatment of patients with germline BRCA-mutated, HER2-negative, high-risk early breast cancer who have previously been treated with neoadjuvant or adjuvant chemotherapy. Maximum duration of treatment: 1 year.
| MAF | $ 1,600 | $ 600 | 8 |
Ovarian cancer |
Olaparib |
Olaparib tablet (100 mg, 150 mg) |
Lynparza |
Maintenance monotherapy for patients with advanced BRCA-mutated high-grade epithelial ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to first-line platinum-based chemotherapy. Treatment should be continued until disease progression or unacceptable toxicity or a maximum of 24 months. |
MAF |
$ 1,600 |
$ 600 |
8 |
Ovarian cancer |
Olaparib |
Olaparib tablet (100 mg, 150 mg) |
Lynparza |
Maintenance monotherapy for patients with platinum-sensitive relapsed BRCA-mutated high-grade epithelial ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy. Patients must not have received prior treatment with a PARP inhibitor for ovarian cancer. Treatment should be continued until disease progression or unacceptable toxicity. |
MAF |
$ 1,600 |
$ 600 |
8 |
Ovarian cancer |
Olaparib plus bevacizumab biosimilar |
Olaparib tablet (100 mg, 150 mg)
Bevacizumab biosimilar concentrate for solution for infusion (100 mg/4 mL, 400 mg/16 mL) |
Lynparza
Mvasi
|
Olaparib in combination with bevacizumab biosimilar (subsidised brand) as maintenance treatment of patients with advanced homologous recombination deficiency (HRD) positive high-grade epithelial ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to first-line platinum-based chemotherapy in combination with bevacizumab biosimilar. Treatment with olaparib should be continued until disease progression or unacceptable toxicity or for a maximum of 24 months. |
MAF |
$ 2,600 |
$ 600 |
13 |
Pancreatic cancer |
Olaparib |
Olaparib tablet (100 mg, 150 mg) |
Lynparza |
Maintenance treatment of patients with deleterious or suspected deleterious germline BRCA mutated metastatic pancreatic adenocarcinoma whose disease has not progressed on at least 16 weeks of a first-line platinum-based chemotherapy regimen. |
MAF |
$ 1,600 |
$ 600 |
8 |
Prostate cancer |
Olaparib |
Olaparib tablet (100 mg, 150 mg) |
Lynparza |
Treatment of patients with metastatic castration-resistant prostate cancer and homologous recombination repair gene BRCA1/2 and/or ATM-mutations (germline and/or somatic) whose disease has progressed following prior treatment with abiraterone or a second-generation anti-androgen. Androgen deprivation therapy (ADT) should be continued. |
MAF |
$ 1,600 |
$ 600 |
8 |
Ovarian cancer | Olaparib | Olaparib tablet (100 mg, 150 mg) | Lynparza
| Maintenance monotherapy for patients with platinum-sensitive relapsed high- grade epithelial ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy. Patients must not have received prior treatment with a PARP inhibitor for ovarian cancer. Treatment should be continued until disease progression or unacceptable toxicity.
| No subsidy | $ 1,600 | $ 600 | 8 |
Ovarian cancer |
Olaparib plus bevacizumab |
Olaparib tablet (100 mg, 150 mg)
Bevacizumab concentrate for solution for infusion (100 mg/4 mL, 400 mg/16 mL) |
Lynparza
Avastin Vegzelma |
Olaparib in combination with bevacizumab (non-subsidised brand) as maintenance treatment of patients with advanced homologous recombination deficiency (HRD) positive high-grade epithelial ovarian, fallopian tube or primary peritoneal cancer who are in complete or partial response to first-line platinum-based chemotherapy in combination with bevacizumab. Treatment with olaparib should be continued until disease progression or unacceptable toxicity or for a maximum of 24 months. |
No subsidy |
$ 2,600 |
$ 600 |
13 |
Lung cancer |
Osimertinib |
Osimertinib tablet (40 mg, 80 mg) |
Tagrisso |
Treatment of patients with locally advanced or metastatic EGFR T790M mutation-positive non-small-cell lung cancer whose disease has progressed on or after EGFR TKI therapy. For patients with isolated brain metastases who are clinically ineligible for re-biopsy and where T790M cannot be confirmed, osimertinib may be used until progression. |
MAF |
$ 2,400 |
$ 600 |
12 |
Lung cancer |
Osimertinib |
Osimertinib tablet (40 mg, 80 mg) |
Tagrisso |
Adjuvant treatment after tumour resection in patients with stage IB to IIIA non-small-cell lung cancer (NSCLC) whose tumours have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations. Treatment should be continued until disease recurrence or unacceptable toxicity or for a maximum of 3 years. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Lung cancer |
Osimertinib |
Osimertinib tablet (40 mg, 80 mg) |
Tagrisso |
For newly diagnosed locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer, including patients who have developed intolerance to another EGFR tyrosine kinase inhibitor of a severity necessitating permanent treatment withdrawal.
|
No subsidy |
$ 2,400 |
$ 600 |
12 |
Others |
Oxaliplatin |
Oxaliplatin injection (50 mg, 100 mg, 200 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Paclitaxel |
Paclitaxel vial (150 mg/25 mL, 300 mg/50 mL) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Breast cancer |
Palbociclib |
Palbociclib capsule (75 mg, 100 mg, 125 mg) and tablet (75 mg, 100 mg, 125 mg) |
- |
Palbociclib in combination with an aromatase inhibitor as initial endocrine-based therapy for HR positive, HER2 negative, advanced or metastatic breast cancer. Pre/perimenopausal women treated with this combination could also receive a luteinizing hormone-releasing hormone agonist according to local clinical practice. |
MAF |
$ 800 |
$ 600 |
4 |
Breast cancer |
Palbociclib |
Palbociclib capsule (75 mg, 100 mg, 125 mg) and tablet (75 mg, 100 mg, 125 mg) |
- |
Palbociclib in combination with fulvestrant for treating HR positive, HER2 negative, advanced or metastatic breast cancer in patients who have received prior endocrine therapy. Pre/perimenopausal women treated with this combination could also receive a luteinizing hormone-releasing hormone agonist according to local clinical practice. |
MAF |
$ 800 |
$ 600 |
4 |
Others |
Panitumumab |
Panitumumab concentrate for solution for infusion (100 mg/5 mL) |
Vectibix |
For cancer treatment. |
SDL |
$ 1,000 |
$ 600 |
5 |
Others |
Pazopanib |
Pazopanib tablet (200 mg, 400 mg) |
- |
For cancer treatment. |
SDL |
$ 1,600 |
$ 600 |
8 |
Others | Pegaspargase | Pegaspargase powder for solution for injection/ infusion (750 U/mL) | Oncaspar | For cancer treatment. | SDL | $ 3,000 | $ 600 | 15 |
Bladder cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of patients with locally advanced or metastatic urothelial carcinoma (UC) after receiving platinum-containing chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for locally advanced or metastatic UC. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Breast cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Pembrolizumab in combination with chemotherapy for the treatment of patients with locally recurrent unresectable or metastatic triple negative breast cancer whose tumours express PD-L1 (CPS ≥10) and who have not received prior chemotherapy for metastatic disease. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Colorectal cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
For untreated metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Head and neck cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Monotherapy for untreated unresectable, recurrent or metastatic squamous cell cancer of the head and neck (RMSCCHN) with PD-L1 CPS≥1. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Head and neck cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Pembrolizumab in combination with platinum-based chemotherapy, for untreated unresectable, recurrent or metastatic squamous cell cancer of the head and neck (RMSCCHN) with PD-L1 CPS≥1. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
For untreated metastatic non-small cell lung cancer (NSCLC) in patients whose tumours express PD-L1 with a tumour proportion score ≥50%, with no EGFR or ALK genomic tumour aberrations. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Pembrolizumab in combination with platinum-doublet chemotherapy for untreated metastatic squamous non-small cell lung cancer (NSCLC). Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Pembrolizumab in combination with platinum-doublet chemotherapy, for untreated metastatic non-squamous non-small cell lung cancer (NSCLC) in patients with no EGFR or ALK genomic tumour aberrations. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of patients with metastatic non-small cell lung cancer (NSCLC), whose tumours express PD-L1 with a tumour proportion score ≥1% and had disease progression during or following platinum-containing chemotherapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for metastatic NSCLC. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of patients with relapsed or refractory classical Hodgkin lymphoma (cHL), who have failed autologous stem cell transplant (ASCT) or following at least two prior therapies when ASCT is not a treatment option. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for this condition in the relapsed or refractory setting. Treatment with pembrolizumab should be stopped at 2 years, or earlier if the person has a stem cell transplant or the disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
MAF |
$ 1,800 |
$ 600 |
9 |
Skin cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Adjuvant treatment of completely resected malignant melanoma in patients with lymph node involvement. Maximum duration of treatment: 12 months. |
MAF |
$ 1,800 |
$ 600 |
9 |
Skin cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of advanced unresectable or metastatic malignant melanoma. Patients must not have received a PD-1 inhibitor or ipilimumab for advanced unresectable or metastatic malignant melanoma. |
MAF |
$ 1,800 |
$ 600 |
9 |
Upper gastrointestinal cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Pembrolizumab in combination with fluoropyrimidine and platinum-based chemotherapy for untreated, locally advanced unresectable or metastatic carcinoma of the oesophagus or HER2 negative gastroesophageal junction (GEJ) adenocarcinoma (tumours with epicenter 1 to 5 cm above the GEJ) that is not amenable to surgical resection or definitive chemoradiation. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. |
MAF |
$ 1,800 |
$ 600 |
9 |
Bladder cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of patients with locally advanced or metastatic urothelial carcinoma who are not eligible for any platinum-containing chemotherapy regardless of PD-L1 status. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Bladder cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of patients with locally advanced or metastatic urothelial carcinoma whose tumours express PD-L1 with a combined positive score (CPS) ≥10, and who are not eligible for cisplatin-containing chemotherapy. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Breast cancer | Pembrolizumab | Pembrolizumab solution for infusion (100 mg/4 mL)
| Keytruda | Pembrolizumab in combination with chemotherapy as neoadjuvant treatment, and then continued as adjuvant monotherapy after surgery, for previously untreated high-risk, early-stage triple-negative breast cancer. Treatment with pembrolizumab should be stopped after a maximum duration of 1 year across neoadjuvant and adjuvant phases, or earlier if disease progresses or recurs.
| No subsidy | $ 1,800 | $ 600 | 9 |
Cervical cancer | Pembrolizumab | Pembrolizumab solution for infusion (100 mg/4 mL) | Keytruda | Pembrolizumab, in combination with chemotherapy, for treating patients with persistent, recurrent, or metastatic cervical cancer whose tumours express PD-L1 with a CPS ≥1. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression.
| No subsidy | $ 1,800 | $ 600 | 9 |
Cervical cancer | Pembrolizumab | Pembrolizumab solution for infusion (100 mg/4 mL)
| Keytruda | Pembrolizumab, in combination with chemotherapy and bevacizumab, for treating patients with persistent, recurrent, or metastatic cervical cancer whose tumours express PD-L1 with a CPS ≥1. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression.
| No subsidy | $ 1,800 | $ 600 | 9 |
Liver cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of advanced unresectable hepatocellular carcinoma (HCC) in patients with disease progression after 1 or more prior lines of systemic therapy, and who have adequate liver function as assessed by the Child-Pugh scoring system. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for advanced unresectable HCC. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of patients with refractory primary mediastinal B-cell lymphoma (PMBCL), or who have relapsed after 2 or more prior lines of therapy. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for PMBCL. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Merkel cell cancer |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of metastatic Merkel cell carcinoma. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Renal cancer | Pembrolizumab | Pembrolizumab solution for infusion (100 mg/4 mL)
| Keytruda | Adjuvant treatment of patients with renal cell carcinoma at increased risk of recurrence following nephrectomy or following nephrectomy and resection of metastatic lesions. Maximum duration of treatment: 12 months.
| No subsidy | $ 1,800 | $ 600 | 9 |
Tumour agnostic |
Pembrolizumab |
Pembrolizumab solution for infusion (100 mg/4 mL) |
Keytruda |
Treatment of patients with unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) solid tumours that have progressed following prior treatment and who have no satisfactory alternative treatment options. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for the same MSI-H or dMMR solid tumour in the unresectable or metastatic setting. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Renal cancer |
Pembrolizumab plus axitinib |
Pembrolizumab solution for infusion (100 mg/4 mL) Axitinib tablet (1 mg, 5 mg) |
Keytruda Inlyta |
Pembrolizumab in combination with axitinib for untreated advanced renal cell carcinoma. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Endometrial cancer |
Pembrolizumab plus lenvatinib |
Pembrolizumab solution for infusion (100 mg/4 mL) Lenvatinib capsule (4 mg, 10 mg) |
Keytruda Lenvima |
Pembrolizumab in combination with lenvatinib for the treatment of patients with advanced endometrial carcinoma (EC) that is not microsatellite instability-high (non-MSI-H) or mismatch repair deficient (non-dMMR), who have disease progression following prior platinum chemotherapy and are not candidates for curative surgery or radiation. Patients must not have received prior treatment with a PD-1/PD-L1 inhibitor for advanced EC. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment, with or without lenvatinib, is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Renal cancer | Pembrolizumab plus lenvatinib
| Pembrolizumab solution for infusion (100 mg/4 mL)
Lenvatinib capsule (4 mg, 10 mg)
| Keytruda
Lenvima
| Pembrolizumab in combination with lenvatinib for untreated advanced renal cell carcinoma. Treatment with pembrolizumab should be stopped at 2 years, or earlier if disease progresses. Pembrolizumab retreatment, with or without lenvatinib, is allowed at time of progression for up to 1 additional year if the initial treatment was stopped for reasons other than disease progression.
| No subsidy | $ 3,000
| $ 600
| 15 |
Others |
Pemetrexed |
Pemetrexed injection (100 mg, 500 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Upper gastrointestinal cancer | Pemigatinib | Pemigatinib tablet (4.5 mg, 9 mg, 13.5 mg)
| Pemazyre | Treatment of patients with locally advanced or metastatic cholangiocarcinoma with a FGFR2 fusion or rearrangement that has progressed after at least one prior line of systemic therapy.
| No subsidy | $ 1,800
| $ 600
| 9 |
Breast cancer |
Pertuzumab plus trastuzumab |
Pertuzumab concentrate for solution for infusion (420 mg/14 mL)
Trastuzumab powder for IV infusion (440 mg)
Trastuzumab solution for SC injection (600 mg/5 mL) |
Perjeta
Herceptin Ogivri Herzuma Kanjinti Trazimera |
Pertuzumab in combination with trastuzumab and chemotherapy for HER2 positive metastatic or locally recurrent breast cancer, in patients without prior treatment for metastatic disease. Treatment with pertuzumab should be stopped if disease progresses. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Breast cancer |
Pertuzumab plus trastuzumab |
Pertuzumab concentrate for solution for infusion (420 mg/14 mL)
Trastuzumab powder for IV infusion (440 mg)
Trastuzumab solution for SC injection (600 mg/5 mL) |
Perjeta
Herceptin Ogivri Herzuma Kanjinti Trazimera |
Pertuzumab in combination with trastuzumab and chemotherapy for adjuvant treatment of high-risk (with positive nodes) HER2 positive early breast cancer for a maximum duration of 1 year. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Breast cancer |
Pertuzumab plus trastuzumab |
Pertuzumab concentrate for solution for infusion (420 mg/14 mL)
Trastuzumab powder for IV infusion (440 mg)
Trastuzumab solution for SC injection (600 mg/5 mL) |
Perjeta
Herceptin Ogivri Herzuma Kanjinti Trazimera |
Pertuzumab in combination with trastuzumab and chemotherapy for neoadjuvant treatment of HER2 positive locally advanced, inflammatory or early stage (tumour >2 cm in diameter or node positive) breast cancer for 4 to 6 cycles. Following surgery, patients may continue with trastuzumab with or without pertuzumab for a total of 1 year of anti-HER2 treatment. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Breast cancer |
Pertuzumab + Trastuzumab |
Pertuzumab + trastuzumab fixed dose combination injection (1200 mg/600 mg and 600 mg/600 mg) |
Phesgo |
Fixed-dose pertuzumab and trastuzumab subcutaneous injection in combination with chemotherapy for treating HER2-positive metastatic or locally recurrent breast cancer, in patients without prior treatment for metastatic disease. Treatment with pertuzumab should be stopped if disease progresses. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Breast cancer |
Pertuzumab + Trastuzumab |
Pertuzumab + trastuzumab fixed dose combination injection (1200 mg/600 mg and 600 mg/600 mg) |
Phesgo |
Fixed-dose pertuzumab and trastuzumab subcutaneous injection in combination with chemotherapy for adjuvant treatment of high-risk (with positive nodes) HER2-positive early breast cancer for a maximum duration of 1 year. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Breast cancer |
Pertuzumab + Trastuzumab |
Pertuzumab + trastuzumab fixed dose combination injection (1200 mg/600 mg and 600 mg/600 mg) |
Phesgo |
Fixed-dose pertuzumab and trastuzumab subcutaneous injection in combination with chemotherapy for neoadjuvant treatment of HER2-positive locally advanced, inflammatory or early stage (tumour >2 cm in diameter or node positive) breast cancer for 4 to 6 cycles. Following surgery, patients may continue with trastuzumab with or without pertuzumab for a total of 1 year of anti-HER2 treatment. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Lymphoma | Polatuzumab vedotin plus rituximab biosimilar | Polatuzumab vedotin powder for concentrate for solution for infusion (30 mg, 140 mg)
Rituximab biosimilar concentrate for infusion (100 mg/10 mL, 500 mg/50 mL)
| Polivy
Truxima | Polatuzumab in combination with rituximab biosimilar (subsidised brand), cyclophosphamide, doxorubicin, and prednisone for previously untreated diffuse large B-cell lymphoma (DLBCL) in patients with an international prognostic index (IPI) score of 3 to 5.
| MAF | $ 3,400 | $ 600 | 17 |
Lymphoma | Polatuzumab vedotin plus rituximab
| Polatuzumab vedotin powder for concentrate for solution for infusion (30 mg, 140 mg)
Rituximab concentrate for infusion (100 mg/10 mL, 500 mg/50 mL)
| Polivy
MabThera Rixathon | Polatuzumab in combination with rituximab (non-subsidised brand), cyclophosphamide, doxorubicin, and prednisone for previously untreated diffuse large B-cell lymphoma (DLBCL) in patients with an international prognostic index (IPI) score of 3 to 5.
| No subsidy | $ 3,000 | $ 600 | 15 |
Lymphoma | Polatuzumab vedotin plus rituximab
| Polatuzumab vedotin powder for concentrate for solution for infusion (30 mg, 140 mg)
Rituximab concentrate for infusion (100 mg/10 mL, 500 mg/50 mL) | Polivy
MabThera Rixathon Truxima | Polatuzumab in combination with rituximab, cyclophosphamide, doxorubicin, and prednisone for previously untreated diffuse large B-cell lymphoma (DLBCL).
| No subsidy | $ 3,000 | $ 600 | 15 |
Multiple myeloma |
Pomalidomide |
Pomalidomide capsule (1 mg, 2 mg, 3 mg, 4 mg) |
Pomalyst |
Pomalidomide in combination with bortezomib or cyclophosphamide, plus dexamethasone, for patients with multiple myeloma who have received at least one prior therapy. |
MAF |
$ 2,000 |
$ 600 |
10 |
Multiple myeloma |
Pomalidomide |
Pomalidomide capsule (1 mg, 2 mg, 3 mg, 4 mg) |
Pomalyst |
Pomalidomide in combination with dexamethasone for patients with multiple myeloma who have received at least two prior therapies, including both lenalidomide and bortezomib, and have demonstrated disease progression on the last therapy. |
MAF |
$ 2,000 |
$ 600 |
10 |
Leukaemia |
Ponatinib |
Ponatinib tablet (15 mg) |
Iclusig |
Treatment of chronic, accelerated, or blast phase chronic myeloid leukaemia (CML) in patients: • whose disease is resistant to imatinib or dasatinib or nilotinib, and who have the T315I mutation OR • whose disease is resistant to both nilotinib and dasatinib OR • whose disease is resistant to nilotinib or dasatinib and who are intolerant of/contraindicated to the other drug. |
MAF |
$ 1,200 |
$ 600 |
6 |
Leukaemia |
Ponatinib |
Ponatinib tablet (15 mg) |
Iclusig |
Treatment of patients with Philadelphia chromosome positive acute lymphoblastic leukaemia who are resistant to dasatinib; who are intolerant to dasatinib and for whom subsequent treatment with imatinib is not clinically appropriate; or who have the T315I mutation. |
MAF |
$ 1,200 |
$ 600 |
6 |
Others |
Prednisolone |
Prednisolone tablet (1 mg, 5 mg, 20 mg) and syrup (10 mg/5 mL) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Procarbazine |
Procarbazine capsule (50 mg) |
- |
For cancer treatment. |
SDL |
$ 1000 |
$ 600 |
5 |
Prostate cancer |
Radium-223 |
Radium-223 solution for injection (1100 kBq/mL) |
Xofigo |
Treatment of patients with castration-resistant prostate cancer with symptomatic bone metastases and no known visceral metastatic disease. |
No subsidy |
$ 1,400 |
$ 600 |
7 |
Colorectal cancer |
Ramucirumab |
Ramucirumab concentrate for solution for infusion (100 mg/10 mL, 500 mg/50 mL) |
Cyramza |
Ramucirumab in combination with FOLFIRI for treating metastatic colorectal cancer that has progressed on first-line systemic therapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Liver cancer |
Ramucirumab |
Ramucirumab concentrate for solution for infusion (100 mg/10 mL, 500 mg/50 mL) |
Cyramza |
Treatment of advanced unresectable hepatocellular carcinoma in patients with disease progression after 1 or more prior lines of systemic therapy, and who have serum alpha-fetoprotein (AFP) of ≥400 ng/ml, and have adequate liver function as assessed by the Child-Pugh scoring system. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Upper gastrointestinal cancer |
Ramucirumab |
Ramucirumab concentrate for solution for infusion (100 mg/10 mL, 500 mg/50 mL) |
Cyramza |
Ramucirumab as monotherapy for patients with unresectable locally advanced or metastatic gastric or gastroesophageal junction adenocarcinoma, with disease progression on or after prior fluoropyrimidine- or platinum-containing chemotherapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Upper gastrointestinal cancer |
Ramucirumab |
Ramucirumab concentrate for solution for infusion (100 mg/10 mL, 500 mg/50 mL) |
Cyramza |
Ramucirumab in combination with paclitaxel for patients with unresectable locally advanced or metastatic gastric or gastroesophageal junction adenocarcinoma, with disease progression on or after prior fluoropyrimidine- or platinum-containing chemotherapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Colorectal cancer |
Regorafenib |
Regorafenib tablet (40 mg) |
Stivarga |
Treatment of metastatic colorectal cancer that has been previously treated with or are not considered candidates for, available therapies including fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF therapy, and if RAS wild-type, an anti-EGFR therapy. |
MAF |
$ 1,800 |
$ 600 |
9 |
Liver cancer |
Regorafenib |
Regorafenib tablet (40 mg) |
Stivarga |
Treatment of advanced unresectable hepatocellular carcinoma in patients with disease progression after 1 or more prior lines of systemic therapy, and who have adequate liver function as assessed by the Child-Pugh scoring system. |
MAF |
$ 1,800 |
$ 600 |
9 |
Sarcoma |
Regorafenib |
Regorafenib tablet (40 mg) |
Stivarga |
Treatment of patients with locally advanced, unresectable or metastatic gastrointestinal stromal tumours (GISTs) who have been previously treated with imatinib mesylate. |
MAF |
$ 1,800 |
$ 600 |
9 |
Breast cancer |
Ribociclib |
Ribociclib tablet (200 mg) |
Kisqali |
Ribociclib in combination with an aromatase inhibitor as initial endocrine-based therapy for HR positive, HER2 negative, advanced or metastatic breast cancer. Pre/perimenopausal women treated with this combination could also receive a luteinizing hormone-releasing hormone agonist according to local clinical practice. |
MAF |
$ 800 |
$ 600 |
4 |
Breast cancer |
Ribociclib |
Ribociclib tablet (200 mg) |
Kisqali |
Ribociclib in combination with fulvestrant for HR positive, HER2 negative, advanced or metastatic breast cancer in patients who have received prior endocrine therapy. Pre/perimenopausal women treated with this combination could also receive a luteinizing hormone-releasing hormone agonist according to local clinical practice. |
MAF |
$ 800 |
$ 600 |
4 |
Sarcoma | Ripretinib | Ripretinib tablet (50 mg) | Qinlock | Treatment of patients with advanced gastrointestinal stromal tumours (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib.
| No subsidy | $ 1600 | $ 600 | 8 |
Lymphoma |
Rituximab |
Rituximab solution for subcutaneous injection (1400 mg/11.7 mL) |
MabThera |
Rituximab (subcutaneous) for maintenance treatment of patients with follicular lymphoma who have responded to induction therapy. |
No subsidy |
$ 1,000 |
$ 600 |
5 |
Lymphoma |
Rituximab |
Rituximab solution for subcutaneous injection (1400 mg/11.7 mL) |
MabThera |
Rituximab (subcutaneous) in combination with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP), for the treatment of CD20+ diffuse large B-cell non-Hodgkin lymphoma. |
No subsidy |
$ 1,000 |
$ 600 |
5 |
Lymphoma |
Rituximab |
Rituximab solution for subcutaneous injection (1400 mg/11.7 mL) |
MabThera |
Rituximab (subcutaneous) in combination with cyclophosphamide, vincristine, prednisone (CVP), for the treatment of previously untreated patients with stage III-IV follicular lymphoma. |
No subsidy |
$ 1,000 |
$ 600 |
5 |
Others |
Rituximab |
Rituximab concentrate for infusion (100 mg/10 mL, 500 mg/50 mL) |
MabThera |
For cancer treatment in line with HSA registered indication(s). |
No subsidy |
$ 1,000 |
$ 600 |
5 |
Others | Rituximab biosimilar | Rituximab biosimilar concentrate for infusion (100 mg/10 mL, 500 mg/50 mL) | Rixathon
| For cancer treatment. | No subsidy | $ 1,000 | $ 600 | 5 |
Others |
Rituximab biosimilar |
Rituximab biosimilar concentrate for solution for infusion (100 mg/10 mL, 500 mg/50 mL) |
Truxima |
For cancer treatment. |
SDL (Truxima) |
$ 1,000 |
$ 600 |
5 |
Lymphoma |
Romidepsin |
Romidepsin powder for solution for infusion (10 mg) |
- |
Treatment of cutaneous T-cell lymphoma in patients who have received at least one prior systemic therapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Lymphoma |
Romidepsin |
Romidepsin powder for solution for infusion (10 mg) |
- |
Treatment of peripheral T-cell lymphoma in patients who have received at least one prior therapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Myeloproliferative neoplasms |
Ruxolitinib |
Ruxolitinib tablet (5 mg, 15 mg, 20 mg) |
Jakavi |
Treatment of patients with: 1) intermediate-1 risk myelofibrosis with severe disease-related symptoms or splenomegaly that are resistant, refractory or intolerant to available therapy; or 2) intermediate-2 or high-risk myelofibrosis with disease-related splenomegaly or symptoms. |
MAF |
$ 2,000 |
$ 600 |
10 |
Breast cancer |
Sacituzumab govitecan |
Sacituzumab govitecan powder for solution for infusion (180 mg) |
Trodelvy |
Treatment of unresectable locally advanced or metastatic triple negative breast cancer in patients who have received two or more prior systemic therapies, at least one of them for metastatic disease. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Multiple myeloma | Selinexor | Selinexor tablet (20 mg) | Xpovio | In combination with bortezomib and dexamethasone for the treatment of patients with multiple myeloma who have received at least one prior therapy. | No subsidy | $ 2,000 | $ 600 | 10 |
Multiple myeloma | Selinexor | Selinexor tablet (20 mg) | Xpovio | In combination with dexamethasone for the treatment of patients with relapsed or refractory multiple myeloma who received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody. | No subsidy | $ 2,000 | $ 600 | 10 |
Multicentric Castleman's disease |
Siltuximab |
Siltuximab powder for infusion (100 mg) |
Sylvant |
Treatment of patients with multicentric Castleman’s disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Thyroid cancer |
Sodium iodide |
Sodium iodide [I-131] capsule (37 to 6000 MBq) |
- |
For thyroid residue ablation after surgery of differentiated thyroid cancer, and treatment of iodine-accumulating metastases. |
No subsidy |
$ 1,600 |
$ 600 |
8 |
Neuroendocrine |
Somatropin |
Somatropin prefilled pen (5 mg/1.5 mL, 10 mg/1.5 mL) Somatropin powder and solvent for solution for injection (4 mg, 5.3 mg/mL) Somatropin solution for injection (5.83 mg/mL, 8 mg/mL) |
- |
Replacement therapy in adults with growth hormone deficiency associated with benign or malignant hypothalamic or pituitary neoplasms. |
MAF |
$ 600 |
$ 600 |
3 |
Neuroendocrine | Somatropin | Somatropin solution for injection (5 mg/1.5 mL, 10 mg/1.5 mL) | SciTropin A | For cancer treatment. | SDL (SciTropin A) | $ 400 | $ 600 | 3 |
Others |
Sorafenib |
Sorafenib tablet (200 mg) |
- |
For cancer treatment. |
SDL |
$ 1,200 |
$ 600 |
6 |
Neuroendocrine |
Streptozocin |
Streptozocin injection (1 g) |
Zanosar |
Streptozocin in combination with 5-fluorouracil for inoperable, advanced or metastatic, progressive and/or symptomatic, well-differentiated, G1 or G2 neuroendocrine tumours of pancreatic origin. |
No subsidy |
$ 800 |
$ 600 |
4 |
Others | Sunitinib | Sunitinib capsule (12.5 mg)
| - | For cancer treatment. | SDL | $ 1,600 | $ 600 | 8 |
Others |
Sunitinib |
Sunitinib capsule (25 mg, 37.5 mg, 50 mg) |
- |
For cancer treatment. |
No subsidy |
$ 1,600 |
$ 600 |
8 |
Breast cancer |
Talazoparib |
Talazoparib capsule (0.25 mg, 1 mg) |
Talzenna |
Treatment of germline BRCA-mutated, HER2 negative, locally advanced or metastatic breast cancer in patients previously treated with chemotherapy. |
No subsidy |
$ 1,600 |
$ 600 |
8 |
Others |
Tamoxifen |
Tamoxifen tablet (10 mg, 20 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Tegafur + gimeracil + oteracil |
Tegafur + gimeracil + oteracil potassium capsule (20 mg/5.8 mg/19.6 mg, 25 mg/7.25 mg/24.5 mg) |
TS-ONE |
For cancer treatment. |
No subsidy |
$ 200 |
$ 600 |
1 |
Others |
Temozolomide |
Temozolomide capsule (20 mg, 100 mg) |
- |
For cancer treatment. |
SDL |
$ 1,800 |
$ 600 |
9 |
Lung cancer |
Tepotinib |
Tepotinib tablet (225 mg) |
Tepmetko |
Treatment of metastatic non-small cell lung cancer (NSCLC) with mesenchymal-epithelial transition factor gene exon 14 skipping (METex14sk) alterations. |
MAF |
$ 1,600 |
$ 600 |
8 |
Others |
Thalidomide |
Thalidomide capsule (50 mg) |
- |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Others | Thiotepa | Thiotepa injection (15 mg, 100 mg) | Tepadina | In combination with other chemotherapy medicinal products with or without total body irradiation (TBI), as conditioning treatment prior to allogeneic or autologous haematopoietic progenitor cell transplantation (HPCT) in haematological diseases. | No subsidy | $ 3,000 | $ 600 | 15 |
Others |
Tioguanine |
Tioguanine tablet (40 mg) |
- |
For cancer treatment. |
SDL |
$ 1,600 |
$ 600 |
8 |
Others |
Topotecan |
Topotecan injection (4 mg) |
- |
For cancer treatment. |
No subsidy |
$ 200 |
$ 600 |
1 |
Sarcoma |
Trabectedin |
Trabectedin powder for injection (1 mg) |
Yondelis |
Treatment of patients with advanced or metastatic soft tissue sarcoma, after failure of anthracyclines and ifosfamide (unless unsuitable). |
No subsidy |
$ 1,200 |
$ 600 |
6 |
Others |
Trastuzumab | Trastuzumab powder for IV infusion (440 mg) |
Herceptin |
For cancer treatment in line with HSA registered indication(s). |
No subsidy |
$ 600 |
$ 600 |
3 |
Others | Trastuzumab biosimilar | Trastuzumab biosimilar powder for IV infusion (440 mg)
| Kanjinti Trazimera
| For cancer treatment. | No subsidy | $ 600 | $ 600 | 3 |
Others |
Trastuzumab |
Trastuzumab solution for SC injection (600 mg/5 mL) |
Herceptin | For cancer treatment in line with HSA registered indication(s). |
No subsidy |
$ 600 |
$ 600 |
3 |
Others |
Trastuzumab biosimilar |
Trastuzumab biosimilar powder for IV infusion (440 mg) |
Ogivri Herzuma |
For cancer treatment. |
SDL (Ogivri, Herzuma) |
$ 600 |
$ 600 |
3 |
Breast cancer | Trastuzumab deruxtecan
| Trastuzumab deruxtecan powder for concentrate for solution for infusion (100 mg) | Enhertu | Treatment of patients with unresectable or metastatic HER2-positive breast cancer who have received a prior anti-HER2-based regimen. | No subsidy | $ 2,400 | $ 600 | 12 |
Upper gastrointestinal cancer | Trastuzumab deruxtecan
| Trastuzumab deruxtecan powder for concentrate for solution for infusion (100 mg)
| Enhertu
| Treatment of HER-2 positive locally advanced or metastatic gastric or gastroesophageal junction adenocarcinoma in patients who have received two or more prior regimens, including a trastuzumab-based regimen.
| No subsidy | $ 2,400
| $ 600 | 12 |
Breast cancer |
Trastuzumab emtansine |
Trastuzumab emtansine powder for concentrate for solution for infusion (100 mg, 160 mg) |
Kadcyla |
Adjuvant treatment of HER2 positive early breast cancer in patients with residual invasive disease, after neoadjuvant treatment with trastuzumab and a taxane. Maximum 14 cycles. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Breast cancer |
Trastuzumab emtansine |
Trastuzumab emtansine powder for concentrate for solution for infusion (100 mg, 160 mg) |
Kadcyla |
Treatment of HER2 positive, locally advanced, unresectable, or metastatic breast cancer in patients who have received prior treatment with trastuzumab and chemotherapy. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Others | Treosulfan | Treosulfan powder for solution for infusion (1 g, 5 g) | Trecondi | In combination with fludarabine as part of conditioning treatment prior to allogeneic haematopoietic stem cell transplantation (allo-HSCT) in adult patients with acute myeloid leukaemia (AML) or myelodysplastic syndrome (MDS) at increased risk of toxicity with standard conditioning therapies, and in paediatric patients older than one month with malignant diseases.
| No subsidy | $ 3,000 | $ 600 | 15 |
Others |
Tretinoin |
Tretinoin capsule (10 mg) |
Vesanoid |
For cancer treatment. |
SDL |
$ 800 |
$ 600 |
4 |
Colorectal cancer |
Trifluridine + tipiracil |
Trifluridine + tipiracil tablet (15 mg/6.14 mg, 20 mg/8.19 mg) |
Lonsurf |
Treatment of metastatic colorectal cancer that has been previously treated with, or are not considered candidates for, available therapies including fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF therapy, and if RAS wild-type, an anti-EGFR therapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Upper gastrointestinal cancer |
Trifluridine + tipiracil |
Trifluridine + tipiracil tablet (15 mg/6.14 mg, 20 mg/8.19 mg) |
Lonsurf |
Treatment of patients with unresectable locally advanced or recurrent gastric or gastroesophageal junction adenocarcinoma after 2 or more prior systemic therapies. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Prostate cancer |
Triptorelin |
Triptorelin injection (3.75 mg, 11.25 mg, 22.5 mg) |
- |
Treatment of locally advanced or metastatic prostate cancer. |
No subsidy |
$ 200 |
$ 600 |
1 |
Breast cancer |
Tucatinib plus trastuzumab |
Tucatinib tablet (50 mg, 150 mg)
Trastuzumab powder for IV infusion (440 mg)
Trastuzumab solution for SC injection (600 mg/5 mL) |
Tukysa
Herceptin Ogivri Herzuma Kanjinti Trazimera |
For the treatment of locally advanced unresectable or metastatic HER2-positive breast cancer in combination with trastuzumab and capecitabine in patients who have received one or more prior anti-HER2-based regimens in the metastatic setting. |
No subsidy |
$ 2,400 |
$ 600 |
12 |
Leukaemia |
Venetoclax |
Venetoclax tablet (10 mg, 50 mg, 100 mg) |
Venclexta |
Monotherapy for patients with chronic lymphocytic leukaemia (CLL) who are unsuitable for fludarabine-based therapy, following combination treatment with obinutuzumab. (Maximum treatment duration of obinutuzumab is 6 cycles and venetoclax is 12 months) |
MAF |
$ 3,000 |
$ 600 |
15 |
Leukaemia |
Venetoclax plus rituximab |
Venetoclax tablet (10 mg, 50 mg, 100 mg)
Rituximab biosimilar concentrate for infusion (100 mg/10 mL, 500 mg/50 mL) |
Venclexta
Truxima |
Venetoclax in combination with rituximab biosimilar (subsidised brand) for patients with chronic lymphocytic leukaemia (CLL) who have received at least one prior therapy. Maximum treatment duration of rituximab is 6 cycles and venetoclax is 24 months. |
MAF |
$ 3,800 |
$ 600 |
19 |
Leukaemia |
Venetoclax |
Venetoclax tablet (10 mg, 50 mg, 100 mg) |
Venclexta |
Treatment of newly diagnosed acute myeloid leukaemia (AML) in combination with a hypomethylating agent or low-dose cytarabine in patients who are ineligible for intensive chemotherapy. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Leukaemia |
Venetoclax plus rituximab |
Venetoclax tablet (10 mg, 50 mg, 100 mg)
Rituximab concentrate for infusion (100 mg/10 mL, 500 mg/50 mL) |
Venclexta
MabThera Rixathon |
Venetoclax in combination with rituximab (non-subsidised brand) for patients with chronic lymphocytic leukaemia (CLL) who have received at least one prior therapy. Maximum treatment duration of rituximab is 6 cycles and venetoclax is 24 months. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Leukaemia |
Venetoclax plus obinutuzumab |
Venetoclax tablet (10 mg, 50 mg, 100 mg) Obinutuzumab concentrate for solution for infusion (1000 mg/40 mL) |
Venclexta Gazyva |
Venetoclax in combination with obinutuzumab for patients with previously untreated chronic lymphocytic leukaemia (CLL) who are unsuitable for fludarabine-based therapy. Maximum treatment duration of obinutuzumab is 6 cycles and venetoclax is 12 months. |
MAF |
$ 5,400 |
$ 600 |
27 |
Others |
Vinblastine sulfate |
Vinblastine sulfate vial (10 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Others |
Vincristine sulfate |
Vincristine sulfate vial (1 mg) |
- |
For cancer treatment. |
SDL |
$ 200 |
$ 600 |
1 |
Bladder cancer |
Vinflunine |
Vinflunine concentrate for solution for infusion (50 mg/2 mL, 100 mg/4 mL, 250 mg/10 mL) |
Javlor |
Treatment of patients with locally advanced or metastatic urothelial carcinoma who have received prior platinum-containing chemotherapy. |
No subsidy |
$ 1,800 |
$ 600 |
9 |
Others |
Vinorelbine |
Vinorelbine injection (50 mg/5 mL) |
- |
For cancer treatment. |
SDL |
$ 400 |
$ 600 |
2 |
Others
| Vinorelbine
| Vinorelbine injection (10 mg/ mL)
| - | For cancer treatment. | No subsidy | $ 400
| $ 600
| 2 |
Breast cancer |
Vinorelbine |
Vinorelbine capsule (20 mg, 30 mg) |
- |
Treatment of advanced breast cancer. |
No subsidy |
$ 400 |
$ 600 |
2 |
Lung cancer |
Vinorelbine |
Vinorelbine capsule (20 mg, 30 mg) |
- |
Treatment of non-small cell lung cancer. |
No subsidy |
$ 400 |
$ 600 |
2 |
Skin cancer |
Vismodegib |
Vismodegib capsule (150 mg) |
Erivedge |
Treatment of adults with metastatic basal cell carcinoma, or with locally advanced basal cell carcinoma that has recurred following surgery or who are not candidates for surgery and who are not candidates for radiation. |
No subsidy |
$ 3,000 |
$ 600 |
15 |
Lymphoma | Zanubrutinib | Zanubrutinib capsule (80 mg) | Brukinsa | Treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy.
| MAF | $ 2,000 | $ 600 | 10 |
Lymphoma
| Zanubrutinib | Zanubrutinib capsule (80 mg) | Brukinsa | Monotherapy for patients with Waldenstrom’s macroglobulinemia (WM) who have received at least one prior therapy. | MAF | $ 2,000 | $ 600 | 10 |
Lymphoma | Zanubrutinib | Zanubrutinib capsule (80 mg) | Brukinsa | Monotherapy for previously untreated Waldenstrom’s macroglobulinemia (WM) in patients who are unsuitable for chemo-immunotherapy. | MAF | $ 2,000 | $ 600 | 10 |
Lymphoma | Zanubrutinib | Zanubrutinib capsule (80 mg) | Brukinsa
| Monotherapy for relapsed or refractory marginal zone lymphoma (MZL) in patients who have received at least one prior anti-CD20-based regimen. | MAF | $ 2,000 | $ 600 | 10 |
Leukaemia | Zanubrutinib | Zanubrutinib capsule (80 mg) | Brukinsa | Monotherapy for chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) in patients who have received at least one prior therapy. | MAF | $ 2,000 | $ 600 | 10 |
Leukaemia | Zanubrutinib | Zanubrutinib capsule (80 mg) | Brukinsa | Monotherapy for previously untreated chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) in patients who are unsuitable for fludarabine-based therapy. | MAF | $ 2,000 | $ 600 | 10 |